A case of Zollinger Ellison syndrome associated with multifocal hyperplasia (tumorlets) of gastric antral argyrophillic cells was found in an 11 yr old boy. Similar tumorlets were present in the resected proximal duodenum. Histochemical and ultrastructural features indicate that the component cells of the tumorlets had many features characteristic of gastrin containing ''G cells''. There was no evidence of abnormality within the subtotally resected pancreas. Persistent postoperative hypergastrinemia and hyperserotoninemia is thought to be related to residual tumorlets in the part of the duodenum or jejunum left in situ.
|Original language||English (US)|
|Number of pages||6|
|Journal||Archives of Pathology and Laboratory Medicine|
|State||Published - Dec 1 1974|
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Medical Laboratory Technology