TY - JOUR
T1 - Zofenopril after anterior myocardial infarction
AU - Mörike, Klaus
AU - Mikus, Gerd
AU - Gurbel, Paul A.
AU - O'connor, Christopher M.
AU - Chaudhry, G. Muqtada
AU - Haneef, Neenoofar
AU - Borghi, Claudio
AU - Ambrosioni, Ettore
AU - Magnani, Bruno
PY - 1995/6/22
Y1 - 1995/6/22
N2 - To the Editor: In the study of zofenopril reported by Ambrosioni et al. (Jan. 12 issue),1 the subgroup analysis (their Table 5) showed beneficial effects in patients concomitantly treated with calcium-channel blockers during the six-week treatment period. During the observation period, significantly more patients in the zofenopril group (21.1 percent) than in the placebo group (15.9 percent) received calcium-channel blockers (P = 0.02, as shown in their Table 4). This difference raises the possibility that the favorable outcome in the zofenopril group may have been due in part to the calcium-channel blockers. Indeed, the administration of calcium-channel blockers after acute.
AB - To the Editor: In the study of zofenopril reported by Ambrosioni et al. (Jan. 12 issue),1 the subgroup analysis (their Table 5) showed beneficial effects in patients concomitantly treated with calcium-channel blockers during the six-week treatment period. During the observation period, significantly more patients in the zofenopril group (21.1 percent) than in the placebo group (15.9 percent) received calcium-channel blockers (P = 0.02, as shown in their Table 4). This difference raises the possibility that the favorable outcome in the zofenopril group may have been due in part to the calcium-channel blockers. Indeed, the administration of calcium-channel blockers after acute.
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U2 - 10.1056/NEJM199506223322513
DO - 10.1056/NEJM199506223322513
M3 - Letter
C2 - 7760877
AN - SCOPUS:0029037803
SN - 0028-4793
VL - 332
SP - 1715
EP - 1716
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 25
ER -