Zinc supplementation in the management of shigellosis in malnourished children in Bangladesh

S. K. Roy, R. Raqib, W. Khatun, T. Azim, R. Chowdhury, G. J. Fuchs, David Allen Sack

Research output: Contribution to journalArticle

Abstract

Objective: To assess the impact of zinc supplementation on clinical recovery, weight gain and subsequent growth and morbidity in moderately malnourished children with shigellosis. Design: A randomized, double-blind, controlled trial. Setting: Dhaka hospital of ICDDR,B: Centre for Health and Population Research, Dhaka, Bangladesh. Subjects: Fifty-six moderately malnourished children, aged 12-59 months with culture-proven shigellosis. Methods: Subjects were randomly allocated to receive zinc (20mg/day elemental) in multivitamin syrup (intervention) or multivitamin syrup without zinc (control) in two equally divided doses daily for 2 weeks. All children received pivmecillinam in a dose of 15mg/kg every 6h for 5 days. After supplementation, children were followed in their respective homes every 2 weeks for 6 months. Results: Children receiving zinc recovered from acute illness significantly faster than the control children (P

Original languageEnglish (US)
Pages (from-to)849-855
Number of pages7
JournalEuropean Journal of Clinical Nutrition
Volume62
Issue number7
DOIs
StatePublished - Jul 2008
Externally publishedYes

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shigellosis
Bacillary Dysentery
Bangladesh
Zinc
zinc
syrups
Amdinocillin Pivoxil
dosage
Weight Gain
morbidity
weight gain
Morbidity
Health
Growth
Research
Population

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

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Zinc supplementation in the management of shigellosis in malnourished children in Bangladesh. / Roy, S. K.; Raqib, R.; Khatun, W.; Azim, T.; Chowdhury, R.; Fuchs, G. J.; Sack, David Allen.

In: European Journal of Clinical Nutrition, Vol. 62, No. 7, 07.2008, p. 849-855.

Research output: Contribution to journalArticle

Roy, S. K. ; Raqib, R. ; Khatun, W. ; Azim, T. ; Chowdhury, R. ; Fuchs, G. J. ; Sack, David Allen. / Zinc supplementation in the management of shigellosis in malnourished children in Bangladesh. In: European Journal of Clinical Nutrition. 2008 ; Vol. 62, No. 7. pp. 849-855.
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