Zinc status of infants with fetal alcohol syndrome

Farahnak K. Assadi, Mohsen Ziai

Research output: Contribution to journalArticlepeer-review

Abstract

Plasma and urinary zinc levels were examined in 6 infants with fetal alcohol syndrome to determine whether zinc deficiency, if present in fetal alcohol syndrome patients, is secondary to an increased urinary zinc excretion. Six infants born to nonalcoholic mothers served as controls. There was no significant difference in creatinine clearance, urine flow rate, or plasma albumin concentrations between the two groups. Plasma concentrations of zinc were significantly lower in fetal alcohol syndrome patients (62.5 ± 2.8 µg/dl) in comparison to controls (71 ±1.8 µg/dl), (p = 0.0001). Urinary excretion of zinc in fetal alcohol syndrome patients averaged 646 ±125 µg/24 h, significantly higher than in control subjects (76.6 ± 22 µg/24 h), (p = 0.0001). Thus (1) lower plasma zinc levels are present in infants with fetal alcohol syndrome and (2) increased urinary zinc excretion appears to be responsible for decreased plasma zinc concentrations.

Original languageEnglish (US)
Pages (from-to)551-554
Number of pages4
JournalPediatric research
Volume20
Issue number6
DOIs
StatePublished - Jun 1986

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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