Zidovudine and the Natural History of AIDS

Gerd Fätkenheuer, Hartmut Stützer, Bernd Salzberger, Matthias Schrappe, Carol S. Dukes, Daniel J. Sexton, Malcolm C. Pike, Jonathan D. Buckley, James W. Mosley, Richard D. Moore, Julia Hidalgo, Barbara Sugland, Richard E. Chaisson

Research output: Contribution to journalLetterpeer-review


To the Editor: Although the benefits of zidovudine therapy with regard to the clinical status of patients with the acquired immunodeficiency syndrome (AIDS) are well documented,1 the effect of this therapy on survival is as yet unknown. In their retrospective study, Moore et al. (May 16 issue)2 found a significant improvement in the prognosis of persons treated with zidovudine. However, we think there is a bias in their examination that makes it impossible to draw conclusions about the effect of zidovudine. The median survival of patients given a diagnosis of AIDS between April 1987 and June 1989 who never.

Original languageEnglish (US)
Pages (from-to)1311-1313
Number of pages3
JournalNew England Journal of Medicine
Issue number18
StatePublished - Oct 31 1991

ASJC Scopus subject areas

  • Medicine(all)

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