Zidovudine and the Natural History of AIDS

Gerd Fätkenheuer; Hartmut Stützer; Bernd Salzberger; Matthias Schrappe; Carol S. Dukes; Daniel J. Sexton; Malcolm C. Pike; Jonathan D. Buckley; James W. Mosley; Richard D. Moore; Julia Hidalgo; Barbara Sugland; Richard E. Chaisson

doi:10.1056/NEJM199110313251812

Zidovudine and the Natural History of AIDS

Gerd Fätkenheuer, Hartmut Stützer, Bernd Salzberger, Matthias Schrappe, Carol S. Dukes, Daniel J. Sexton, Malcolm C. Pike, Jonathan D. Buckley, James W. Mosley, Richard D. Moore, Julia Hidalgo, Barbara Sugland, Richard E. Chaisson

School of Medicine

Research output: Contribution to journal › Letter › peer-review

3 Scopus citations

Abstract

To the Editor: Although the benefits of zidovudine therapy with regard to the clinical status of patients with the acquired immunodeficiency syndrome (AIDS) are well documented,¹ the effect of this therapy on survival is as yet unknown. In their retrospective study, Moore et al. (May 16 issue)² found a significant improvement in the prognosis of persons treated with zidovudine. However, we think there is a bias in their examination that makes it impossible to draw conclusions about the effect of zidovudine. The median survival of patients given a diagnosis of AIDS between April 1987 and June 1989 who never.

Original language	English (US)
Pages (from-to)	1311-1313
Number of pages	3
Journal	New England Journal of Medicine
Volume	325
Issue number	18
DOIs	https://doi.org/10.1056/NEJM199110313251812
State	Published - Oct 31 1991

ASJC Scopus subject areas

General Medicine

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title = "Zidovudine and the Natural History of AIDS",

abstract = "To the Editor: Although the benefits of zidovudine therapy with regard to the clinical status of patients with the acquired immunodeficiency syndrome (AIDS) are well documented,1 the effect of this therapy on survival is as yet unknown. In their retrospective study, Moore et al. (May 16 issue)2 found a significant improvement in the prognosis of persons treated with zidovudine. However, we think there is a bias in their examination that makes it impossible to draw conclusions about the effect of zidovudine. The median survival of patients given a diagnosis of AIDS between April 1987 and June 1989 who never.",

author = "Gerd F{\"a}tkenheuer and Hartmut St{\"u}tzer and Bernd Salzberger and Matthias Schrappe and Dukes, {Carol S.} and Sexton, {Daniel J.} and Pike, {Malcolm C.} and Buckley, {Jonathan D.} and Mosley, {James W.} and Moore, {Richard D.} and Julia Hidalgo and Barbara Sugland and Chaisson, {Richard E.}",

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AU - Fätkenheuer, Gerd

AU - Stützer, Hartmut

AU - Salzberger, Bernd

AU - Schrappe, Matthias

AU - Dukes, Carol S.

AU - Sexton, Daniel J.

AU - Pike, Malcolm C.

AU - Buckley, Jonathan D.

AU - Mosley, James W.

AU - Moore, Richard D.

AU - Hidalgo, Julia

AU - Sugland, Barbara

AU - Chaisson, Richard E.

PY - 1991/10/31

Y1 - 1991/10/31

N2 - To the Editor: Although the benefits of zidovudine therapy with regard to the clinical status of patients with the acquired immunodeficiency syndrome (AIDS) are well documented,1 the effect of this therapy on survival is as yet unknown. In their retrospective study, Moore et al. (May 16 issue)2 found a significant improvement in the prognosis of persons treated with zidovudine. However, we think there is a bias in their examination that makes it impossible to draw conclusions about the effect of zidovudine. The median survival of patients given a diagnosis of AIDS between April 1987 and June 1989 who never.

AB - To the Editor: Although the benefits of zidovudine therapy with regard to the clinical status of patients with the acquired immunodeficiency syndrome (AIDS) are well documented,1 the effect of this therapy on survival is as yet unknown. In their retrospective study, Moore et al. (May 16 issue)2 found a significant improvement in the prognosis of persons treated with zidovudine. However, we think there is a bias in their examination that makes it impossible to draw conclusions about the effect of zidovudine. The median survival of patients given a diagnosis of AIDS between April 1987 and June 1989 who never.

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Zidovudine and the Natural History of AIDS

Abstract

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