XI. Antibodies against rotavirus in sera from children living in the Machakos district of Kenya

D. Metselaar, David Allen Sack, A. Z. Kapikian, A. S. Muller

Research output: Contribution to journalArticle

Abstract

207 sera from children under 5 years of age and living in the Machakos District in Kenya were tested in the Complement Fixation Test for antibodies against rotavirus. Two different antigens were used. The superiority of 'O' antigen over Nebraska calf diarrhoea virus antigen was confirmed. After a fall to 29% in the 6-8 months age group, the percentage of children with antibodies quickly rises with age to 80% at the age of 24 months and to practically 100% at the age of 30 months. This age-immunity curve suggests that the majority of children contract infections with rotavirus between 6 and 23 months of age. This conforms to the pattern usually found in temperate climate countries.

Original languageEnglish (US)
Pages (from-to)531-535
Number of pages5
JournalTropical and Geographical Medicine
Volume30
Issue number4
StatePublished - 1978
Externally publishedYes

Fingerprint

Rotavirus
Kenya
Antibodies
Serum
Rotavirus Infections
Antigens
Complement Fixation Tests
O Antigens
Contracts
Climate
Diarrhea
Immunity
Age Groups
Viruses

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health

Cite this

XI. Antibodies against rotavirus in sera from children living in the Machakos district of Kenya. / Metselaar, D.; Sack, David Allen; Kapikian, A. Z.; Muller, A. S.

In: Tropical and Geographical Medicine, Vol. 30, No. 4, 1978, p. 531-535.

Research output: Contribution to journalArticle

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