TY - JOUR
T1 - Workshop on HIV infection and aging
T2 - What is known and future research directions
AU - Effros, Rita B.
AU - Fletcher, Courtney V.
AU - Gebo, Kelly
AU - Halter, Jeffrey B.
AU - Hazzard, William R.
AU - Horne, Frances Mc Farland
AU - Huebner, Robin E.
AU - Janoff, Edward N.
AU - Justice, Amy C.
AU - Kuritzkes, Daniel
AU - Nayfield, Susan G.
AU - Plaeger, Susan F.
AU - Schmader, Kenneth E.
AU - Ashworth, John R.
AU - Campanelli, Christine
AU - Clayton, Charles P.
AU - Rada, Beth
AU - Woolard, Nancy F.
AU - High, Kevin P.
PY - 2008/8/15
Y1 - 2008/8/15
N2 - Highly active antiretroviral treatment has resulted in dramatically increased life expectancy among patients with HIV infection who are now aging while receiving treatment and are at risk of developing chronic diseases associated with advanced age. Similarities between aging and the courses of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome suggest that HIV infection compresses the aging process, perhaps accelerating comorbidities and frailty. In a workshop organized by the Association of Specialty Professors, the Infectious Diseases Society of America, the HIV Medical Association, the National Institute on Aging, and the National Institute on Allergy and Infectious Diseases, researchers in infectious diseases, geriatrics, immunology, and gerontology met to review what is known about HIV infection and aging, to identify research gaps, and to suggest high priority topics for future research. Answers to the questions posed are likely to help prioritize and balance strategies to slow the progression of HIV infection, to address comorbidities and drug toxicity, and to enhance understanding about both HIV infection and aging.
AB - Highly active antiretroviral treatment has resulted in dramatically increased life expectancy among patients with HIV infection who are now aging while receiving treatment and are at risk of developing chronic diseases associated with advanced age. Similarities between aging and the courses of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome suggest that HIV infection compresses the aging process, perhaps accelerating comorbidities and frailty. In a workshop organized by the Association of Specialty Professors, the Infectious Diseases Society of America, the HIV Medical Association, the National Institute on Aging, and the National Institute on Allergy and Infectious Diseases, researchers in infectious diseases, geriatrics, immunology, and gerontology met to review what is known about HIV infection and aging, to identify research gaps, and to suggest high priority topics for future research. Answers to the questions posed are likely to help prioritize and balance strategies to slow the progression of HIV infection, to address comorbidities and drug toxicity, and to enhance understanding about both HIV infection and aging.
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U2 - 10.1086/590150
DO - 10.1086/590150
M3 - Review article
C2 - 18627268
AN - SCOPUS:48749099532
SN - 1058-4838
VL - 47
SP - 542
EP - 553
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 4
ER -