Word production deficits in schizophrenia

Cherie Marvel, Barbara L. Schwartz, Keren L. Isaacs

Research output: Contribution to journalArticle

Abstract

Fronto-cerebellar circuitry is implicated in word production. Data suggest that the cerebellum is involved in word search, whereas the prefrontal cortex underlies the selection of words from among competing alternatives. We explored the role of search and selection processes in word production deficits in schizophrenia patients. In Experiment 1, patients were impaired in a verb generation task under both high and low selection conditions but were more impaired in the high selection condition. In Experiment 2, when the difficulty level of search and selection conditions was equated in a word stem completion task, patients were only impaired in the search condition. Word search deficits underlie word production problems in schizophrenia, and may involve fronto-cerebellar dysfunction.

Original languageEnglish (US)
Pages (from-to)182-191
Number of pages10
JournalBrain and Language
Volume89
Issue number1
DOIs
StatePublished - Apr 2004
Externally publishedYes

Fingerprint

schizophrenia
Schizophrenia
deficit
Cerebellar Diseases
Prefrontal Cortex
Cerebellum
experiment
Word Production
Experiment

Keywords

  • Cerebellum
  • Frontal lobe
  • Language
  • Schizophrenia
  • Search
  • Selection
  • Stem completion
  • Verb generation
  • Word production

ASJC Scopus subject areas

  • Language and Linguistics
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)

Cite this

Word production deficits in schizophrenia. / Marvel, Cherie; Schwartz, Barbara L.; Isaacs, Keren L.

In: Brain and Language, Vol. 89, No. 1, 04.2004, p. 182-191.

Research output: Contribution to journalArticle

Marvel, Cherie ; Schwartz, Barbara L. ; Isaacs, Keren L. / Word production deficits in schizophrenia. In: Brain and Language. 2004 ; Vol. 89, No. 1. pp. 182-191.
@article{ff8dae1d9bd9494e9c4101cafe9ae01c,
title = "Word production deficits in schizophrenia",
abstract = "Fronto-cerebellar circuitry is implicated in word production. Data suggest that the cerebellum is involved in word search, whereas the prefrontal cortex underlies the selection of words from among competing alternatives. We explored the role of search and selection processes in word production deficits in schizophrenia patients. In Experiment 1, patients were impaired in a verb generation task under both high and low selection conditions but were more impaired in the high selection condition. In Experiment 2, when the difficulty level of search and selection conditions was equated in a word stem completion task, patients were only impaired in the search condition. Word search deficits underlie word production problems in schizophrenia, and may involve fronto-cerebellar dysfunction.",
keywords = "Cerebellum, Frontal lobe, Language, Schizophrenia, Search, Selection, Stem completion, Verb generation, Word production",
author = "Cherie Marvel and Schwartz, {Barbara L.} and Isaacs, {Keren L.}",
year = "2004",
month = "4",
doi = "10.1016/S0093-934X(03)00366-3",
language = "English (US)",
volume = "89",
pages = "182--191",
journal = "Brain and Language",
issn = "0093-934X",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - Word production deficits in schizophrenia

AU - Marvel, Cherie

AU - Schwartz, Barbara L.

AU - Isaacs, Keren L.

PY - 2004/4

Y1 - 2004/4

N2 - Fronto-cerebellar circuitry is implicated in word production. Data suggest that the cerebellum is involved in word search, whereas the prefrontal cortex underlies the selection of words from among competing alternatives. We explored the role of search and selection processes in word production deficits in schizophrenia patients. In Experiment 1, patients were impaired in a verb generation task under both high and low selection conditions but were more impaired in the high selection condition. In Experiment 2, when the difficulty level of search and selection conditions was equated in a word stem completion task, patients were only impaired in the search condition. Word search deficits underlie word production problems in schizophrenia, and may involve fronto-cerebellar dysfunction.

AB - Fronto-cerebellar circuitry is implicated in word production. Data suggest that the cerebellum is involved in word search, whereas the prefrontal cortex underlies the selection of words from among competing alternatives. We explored the role of search and selection processes in word production deficits in schizophrenia patients. In Experiment 1, patients were impaired in a verb generation task under both high and low selection conditions but were more impaired in the high selection condition. In Experiment 2, when the difficulty level of search and selection conditions was equated in a word stem completion task, patients were only impaired in the search condition. Word search deficits underlie word production problems in schizophrenia, and may involve fronto-cerebellar dysfunction.

KW - Cerebellum

KW - Frontal lobe

KW - Language

KW - Schizophrenia

KW - Search

KW - Selection

KW - Stem completion

KW - Verb generation

KW - Word production

UR - http://www.scopus.com/inward/record.url?scp=1542298948&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1542298948&partnerID=8YFLogxK

U2 - 10.1016/S0093-934X(03)00366-3

DO - 10.1016/S0093-934X(03)00366-3

M3 - Article

VL - 89

SP - 182

EP - 191

JO - Brain and Language

JF - Brain and Language

SN - 0093-934X

IS - 1

ER -