Widely disseminated Cunninghamella mucormycosis in an adult renal transplant patient: Case report and review of the literature

P. C. Kolbeck, R. G. Makhoul, R. R. Bollinger, F. Sanfilippo

Research output: Contribution to journalArticle

Abstract

A case of widely disseminated mucormycosis involving Cunninghamella bertholletiae is reported. This represent the first report of Cunninghamella infection in a transplant patient and, to our knowledge, only the eighth reported case of human infection by this saprophytic fungus. The clinical course was similar to most of the previously reported cases in that the patient was immunocompromised prior to the infection and the diagnosis was made too late for appropriate therapaeutic intervention. The current case is unique in that it involved a renal allograft recipient; that the major clinical signs and symptoms mimicked myocardial infarction; and that there was more widespread dissemination than in earlier cases. The histologic and laboratory identification of the fungus are presented and correlated with the clinical parameters (signs, symptoms, and therapy) of this case as well as the cases previously reported in the literature.

Original languageEnglish (US)
Pages (from-to)747-753
Number of pages7
JournalAmerican Journal of Clinical Pathology
Volume83
Issue number6
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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