Why is pancreatic cancer so deadly? The pathologist's view

Ralph H Hruban, Matthias M. Gaida, Elizabeth Thompson, Seung Mo Hong, Michaël Noë, Lodewijk A.A. Brosens, Martine Jongepier, G. Johan A. Offerhaus, Laura Delong Wood

Research output: Contribution to journalArticle

Abstract

The remarkable aggressiveness of pancreatic cancer has never been fully explained. Although clearly multifactorial, we postulate that venous invasion, a finding seen in most pancreatic cancers but not in most cancers of other organs, may be a significant, underappreciated contributor to the aggressiveness of this disease.

Original languageEnglish (US)
JournalJournal of Pathology
DOIs
StatePublished - Jan 1 2019

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Pancreatic Neoplasms
Neoplasms
Pathologists

Keywords

  • pancreas
  • pancreas cancer
  • pancreatic cancer
  • prognosis
  • tumor immune microenvironment
  • vein
  • venous invasion

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Why is pancreatic cancer so deadly? The pathologist's view. / Hruban, Ralph H; Gaida, Matthias M.; Thompson, Elizabeth; Hong, Seung Mo; Noë, Michaël; Brosens, Lodewijk A.A.; Jongepier, Martine; Offerhaus, G. Johan A.; Wood, Laura Delong.

In: Journal of Pathology, 01.01.2019.

Research output: Contribution to journalArticle

Hruban, Ralph H ; Gaida, Matthias M. ; Thompson, Elizabeth ; Hong, Seung Mo ; Noë, Michaël ; Brosens, Lodewijk A.A. ; Jongepier, Martine ; Offerhaus, G. Johan A. ; Wood, Laura Delong. / Why is pancreatic cancer so deadly? The pathologist's view. In: Journal of Pathology. 2019.
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