Why does viral RNA sometimes persist after recovery from acute infections?

Research output: Contribution to journalArticlepeer-review

Abstract

AU DNA: viruses often persist in the body of their host, becoming: latent and recurring many months or years later. By contrast, most RNA viruses cause acute infections that are cleared from the host as they lack the mechanisms to persist. However, it is becoming clear that viral RNA can persist after clinical recovery and elimination of detectable infectious virus. This persistence can either be asymptomatic or associated with late progressive disease or nonspecific lingering symptoms, such as may be the case following infection with Ebola or Severe Acute Respiratory Syndrome Coronavirus 2 (SAU ARS-CoV-2).:

Original languageEnglish (US)
Article numbere3001687
JournalPLoS biology
Volume20
Issue number6
DOIs
StatePublished - Jun 2022

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology
  • General Immunology and Microbiology
  • General Neuroscience

Fingerprint

Dive into the research topics of 'Why does viral RNA sometimes persist after recovery from acute infections?'. Together they form a unique fingerprint.

Cite this