Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes

Andrew R. Wood, Marcus A. Tuke, Mike Nalls, Dena Hernandez, J. Raphael Gibbs, Haoxiang Lin, Christopher S. Xu, Qibin Li, Juan Shen, Goo Jun, Marcio Almeida, Toshiko Tanaka, John R B Perry, Kyle Gaulton, Manny Rivas, Richard Pearson, Joanne E. Curran, Matthew P. Johnson, Harald H H Göring, Ravindranath DuggiralaJohn Blangero, Mark I. Mccarthy, Stefania Bandinelli, Anna Murray, Michael N. Weedon, Andrew Singleton, David Melzer, Luigi Ferrucci, Timothy M. Frayling

Research output: Contribution to journalArticlepeer-review

Abstract

Initial results from sequencing studies suggest that there are relatively few low-frequency (

Original languageEnglish (US)
Pages (from-to)1504-1512
Number of pages9
JournalHuman Molecular Genetics
Volume24
Issue number5
DOIs
StatePublished - Mar 1 2015
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)
  • Molecular Biology

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