Whole-cell vaccines

Danijela Jelovac, Leisha A. Emens

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Therapeutic cancer vaccines aim to generate tumor immunity through coordinated cell- and antibody-mediated responses that ultimately result in highly specific and potent T cells capable of destroying cancers. Cancer vaccines have unique advantages compared to most other cancer therapeutics, with a high degree of specificity for tumor cells relative to normal tissues, a highly favorable side-effect profile, and the potential for a long-lasting treatment effect due to immunologic memory.

Original languageEnglish (US)
Title of host publicationCancer Therapeutic Targets
PublisherSpringer New York
Pages561-574
Number of pages14
Volume1-2
ISBN (Electronic)9781441907172
ISBN (Print)9781441907165
DOIs
StatePublished - Jan 1 2017

Keywords

  • Chemotherapy
  • Combination immunotherapy
  • Immune response
  • Immunotherapy
  • Monoclonal antibody
  • Whole-cell vaccine

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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  • Cite this

    Jelovac, D., & Emens, L. A. (2017). Whole-cell vaccines. In Cancer Therapeutic Targets (Vol. 1-2, pp. 561-574). Springer New York. https://doi.org/10.1007/978-1-4419-0717-2_148