@inproceedings{c9c92e1de3504b4ba99891258160d24c,
title = "Whole brain parcellation with pathology: Validation on ventriculomegaly patients",
abstract = "Numerous brain disorders are associated with ventriculomegaly; normal pressure hydrocephalus (NPH) is one example. NPH presents with dementia-like symptoms and is often misdiagnosed as Alzheimer{\textquoteright}s due to its chronic nature and nonspecific presenting symptoms. However, unlike other forms of dementia NPH can be treated surgically with an over 80% success rate on appropriately selected patients. Accurate assessment of the ventricles, in particular its sub-compartments, is required to diagnose the condition. Existing segmentation algorithms fail to accurately identify the ventricles in patients with such extreme pathology. We present an improvement to a whole brain segmentation approach that accurately identifies the ventricles and parcellates them into four sub-compartments. Our work is a combination of patch-based tissue segmentation and multi-atlas registration-based labeling. We include a validation on NPH patients, demonstrating superior performance against state-of-the-art methods.",
keywords = "Brain, Enlarged ventricles, Hydrocephalus, MRI",
author = "Aaron Carass and Muhan Shao and Xiang Li and Dewey, {Blake E.} and Blitz, {Ari M.} and Snehashis Roy and Pham, {Dzung L.} and Prince, {Jerry L.} and Ellingsen, {Lotta M.}",
note = "Publisher Copyright: {\textcopyright} Springer International Publishing AG 2017.; 3rd International Workshop on Patch-Based Techniques in Medical Imaging, Patch-MI 2017 held in conjunction with 20th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2017 ; Conference date: 14-09-2017 Through 14-09-2017",
year = "2017",
doi = "10.1007/978-3-319-67434-6_3",
language = "English (US)",
isbn = "9783319674339",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Verlag",
pages = "20--28",
editor = "Yiqiang Zhan and Wenjia Bai and Guorong Wu and Pierrick Coupe and Munsell, {Brent C.} and Gerard Sanroma",
booktitle = "Patch-Based Techniques in Medical Imaging - 3rd International Workshop, Patch-MI 2017 Held in Conjunction with MICCAI 2017, Proceedings",
}