Abstract
The possible relationship between deep white matter hyperintensity (WMHI) lesions detected by magnetic resonance imaging and response to lithium was examined in 16 patients with bipolar disorder who had been under maintenance treatment with lithium for more than 1 year. Bipolar patients who had higher scores of WMHI responded significantly better to lithium (r = 0.57, P < 0.05) than did those who had lower scores. This preliminary result suggests that the presence of WMHI may be associated with a better response to lithium.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 117-120 |
| Number of pages | 4 |
| Journal | Psychiatry and Clinical Neurosciences |
| Volume | 54 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 2000 |
| Externally published | Yes |
Keywords
- Bipolar disorder
- Brain
- Lithium
- Magnetic resonance imaging
- Treatment response
ASJC Scopus subject areas
- Neuroscience(all)
- Neurology
- Clinical Neurology
- Psychiatry and Mental health