What light scattering can tell about the ordering of collagen fibrils in corneal stroma

Richard A. Farrell, D. E. Freund, Russell L. McCally

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Normal cornea transmits greater than 90% of visible light, but its transmission would be less than 30% if the stroma's collagen fibrils scattered independently of one another. Thus modern transparency theories are based on there being sufficient order in fibril positions for destructive interference to cause cancellation among the scattered fields. Two types of structure have been proposed: long-range crystalline order as used in the earliest theory, and short-range liquid-like order such as that depicted by electron microscopy. Of course structures depicted in electron micrographs may be distorted and other tests are required to determine the nature of the order. Light scattering measurements can afford such a test. Specifically, the two types of order produce different dependencies on wavelength for the scattering cross-section (angular or total) in the long-wavelength limit. Measurements must be analyzed appropriately to obtain the long-wavelength limit. The results reported in this paper demonstrate that measurements of both angular and total scattering cross-sections support short-range order of fibril positions.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherPubl by Society of Photo-Optical Instrumentation Engineers
Pages303-313
Number of pages11
ISBN (Print)0819411116, 9780819411112
DOIs
StatePublished - 1993
EventStatic and Dynamic Light Scattering in Medicine and Biology - Los Angeles, CA, USA
Duration: Jan 21 1993Jan 22 1993

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume1884
ISSN (Print)0277-786X

Other

OtherStatic and Dynamic Light Scattering in Medicine and Biology
CityLos Angeles, CA, USA
Period1/21/931/22/93

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Farrell, R. A., Freund, D. E., & McCally, R. L. (1993). What light scattering can tell about the ordering of collagen fibrils in corneal stroma. In Proceedings of SPIE - The International Society for Optical Engineering (pp. 303-313). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1884). Publ by Society of Photo-Optical Instrumentation Engineers. https://doi.org/10.1117/12.148356