What has gene expression profiling taught us about glaucoma?

Research output: Contribution to journalArticle

Abstract

The availability in recent years of new cellular and animal models, as well as advances in genomic and related technologies, have made possible important advances in our understanding of the cellular and molecular events that mediate retinal ganglion cell dysfunction and death in glaucoma. In this review, we briefly summarize the methodology and results of a number of genome-wide expression studies that have been performed to study the retina and optic nerve head in glaucoma.

Original languageEnglish (US)
Pages (from-to)191-195
Number of pages5
JournalExperimental eye research
Volume93
Issue number2
DOIs
StatePublished - Aug 1 2011

Keywords

  • Apoptosis
  • Gene expression profiling
  • Glaucoma
  • Neuroinflammation
  • Optic nerve injury
  • Retinal ganglion cell

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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