Abstract
While many mechanisms have been proposed for microRNAs (miRNAs) function, most ultimately cause message degradation. A view has emerged that miRNAs silence gene expression by promoting the association of mRNA decay factors. Recent research results, however, suggest that in both zebrafish and fruit fly, translational inhibition is the initiating event of miRNA-mediated gene silencing.
Original language | English (US) |
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Pages (from-to) | 1322-1324 |
Number of pages | 3 |
Journal | Cell Research |
Volume | 22 |
Issue number | 9 |
DOIs | |
State | Published - Sep 2012 |
Externally published | Yes |
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology