Wernicke's encephalopathy: Beyond alcoholism

Robin K. Wilson; Ralph W. Kuncl; Andrea M. Corse

doi:10.1038/ncpneuro0094

Wernicke's encephalopathy: Beyond alcoholism

Robin K. Wilson, Ralph W. Kuncl, Andrea M. Corse

School of Medicine

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Background: A 17-year-old pregnant woman presented to hospital at 19 weeks' gestation with an 8-week history of hyperemesis gravidarum, 16.8 kg of weight loss, and new-onset weakness, dizziness and blurred vision. Examination of the patient showed confusion, papilledema, ophthalmoparesis, nystagmus, reduced hearing and truncal ataxia. Investigations: Physical examination, abdominal ultrasound, fetal ultrasound, brain MRI, magnetic resonance angiography, magnetic resonance venography and cerebrospinal-fluid analysis. Diagnosis: Wernicke's encephalopathy, hyperemesis gravidarum and fetal loss. Management: Intravenous thiamine repletion and elimination of deficiency risk factors.

Original language	English (US)
Pages (from-to)	54-58
Number of pages	5
Journal	Nature Clinical Practice Neurology
Volume	2
Issue number	1
DOIs	https://doi.org/10.1038/ncpneuro0094
State	Published - Jan 1 2006

Keywords

Hyperemesis gravidarum
MRI paraventricular hyperintensities
Thiamine deficiency
Wernick's encephalopathy

ASJC Scopus subject areas

Clinical Neurology
Cellular and Molecular Neuroscience

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10.1038/ncpneuro0094

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AU - Corse, Andrea M.

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AB - Background: A 17-year-old pregnant woman presented to hospital at 19 weeks' gestation with an 8-week history of hyperemesis gravidarum, 16.8 kg of weight loss, and new-onset weakness, dizziness and blurred vision. Examination of the patient showed confusion, papilledema, ophthalmoparesis, nystagmus, reduced hearing and truncal ataxia. Investigations: Physical examination, abdominal ultrasound, fetal ultrasound, brain MRI, magnetic resonance angiography, magnetic resonance venography and cerebrospinal-fluid analysis. Diagnosis: Wernicke's encephalopathy, hyperemesis gravidarum and fetal loss. Management: Intravenous thiamine repletion and elimination of deficiency risk factors.

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Wernicke's encephalopathy: Beyond alcoholism

Abstract

Keywords

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