TY - JOUR
T1 - Well-differentiated papillary mesothelioma occurring in the tunica vaginalis of the testis with contralateral atypical mesothelial hyperplasia
AU - Tolhurst, Stephen R.
AU - Lotan, Tamara
AU - Rapp, David E.
AU - Lyon, Mark B.
AU - Orvieto, Marcelo A.
AU - Gerber, Glenn S.
AU - Sokoloff, Mitchell H.
PY - 2006/1
Y1 - 2006/1
N2 - Well-differentiated papillary mesothelioma (WDPM) occurs rarely in the paratesticular region, with only a handful of published case reports. Often presenting with recurrent hydrocele, WDPM is a multifocal mesothelial proliferation with a predominantly indolent clinical course. Accordingly, pathologic distinction of this lesion from true malignant mesothelioma is crucial, although it may be difficult because of the variability of associated histologic features. In addition, rare cases of WDPM have progressed to malignant mesothelioma, leading to its classification as a tumor of low malignant potential. Here, we report a case of multifocal WDPM occurring in the tunica vaginalis and tunica albuginea, with contralateral atypical mesothelial hyperplasia, a potentially premalignant lesion.
AB - Well-differentiated papillary mesothelioma (WDPM) occurs rarely in the paratesticular region, with only a handful of published case reports. Often presenting with recurrent hydrocele, WDPM is a multifocal mesothelial proliferation with a predominantly indolent clinical course. Accordingly, pathologic distinction of this lesion from true malignant mesothelioma is crucial, although it may be difficult because of the variability of associated histologic features. In addition, rare cases of WDPM have progressed to malignant mesothelioma, leading to its classification as a tumor of low malignant potential. Here, we report a case of multifocal WDPM occurring in the tunica vaginalis and tunica albuginea, with contralateral atypical mesothelial hyperplasia, a potentially premalignant lesion.
KW - Mesothelioma
KW - Orchiectomy
KW - Tunica vaginalis testis
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U2 - 10.1016/j.urolonc.2005.06.021
DO - 10.1016/j.urolonc.2005.06.021
M3 - Article
C2 - 16414491
AN - SCOPUS:30744446975
SN - 1078-1439
VL - 24
SP - 36
EP - 39
JO - Urologic Oncology: Seminars and Original Investigations
JF - Urologic Oncology: Seminars and Original Investigations
IS - 1
ER -