Weight loss causes increased mortality

Cons

D. Yang, K. R. Fontaine, C. Wang, D. B. Allison

Research output: Contribution to journalArticle

Abstract

Short-term studies indicate that intentional weight loss (IWL) among obese persons significantly improves health variables that are often precursors or markers of chronic diseases (e.g. heart diseases, type-2 diabetes). Hence, it is logical to assume that IWL among obese persons would lead to increased longevity. On the whole, epidemiological studies, including recent ones that use conservative analytic approaches such as distinguishing between apparently IWL and unintentional weight loss (UWL), adjusting for potential confounders and excluding apparently unhealthy subjects, indicate that apparently IWL appears to neither increase nor decrease mortality rate. However, it is important to note that none of the existing studies were designed specifically to test the hypothesis that IWL reduces mortality rate, and given methodological problems, these studies do not provide a satisfactory way to address the body mass index (BMI)-mortality question. Several controlled clinical trials suggest that IWL may reduce mortality rate. However, even in these studies, it is important to acknowledge that subjects are randomized to conditions that produce more or less weight loss and not to distinct levels of weight loss per se. Nevertheless, while we await additional data from better designed studies, given our incomplete knowledge, we conclude that it seems more likely than not that IWL achieved by medically recommended methods does not increase and probably decreases mortality rate.

Original languageEnglish (US)
Pages (from-to)9-16
Number of pages8
JournalObesity Reviews
Volume4
Issue number1
DOIs
StatePublished - Feb 2003

Fingerprint

Weight Loss
Mortality
Controlled Clinical Trials
Type 2 Diabetes Mellitus
Epidemiologic Studies
Heart Diseases
Body Mass Index
Chronic Disease
Health

Keywords

  • Intentional weight loss
  • Mortality
  • Obesity

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Endocrinology

Cite this

Yang, D., Fontaine, K. R., Wang, C., & Allison, D. B. (2003). Weight loss causes increased mortality: Cons. Obesity Reviews, 4(1), 9-16. https://doi.org/10.1046/j.1467-789X.2003.00092.x

Weight loss causes increased mortality : Cons. / Yang, D.; Fontaine, K. R.; Wang, C.; Allison, D. B.

In: Obesity Reviews, Vol. 4, No. 1, 02.2003, p. 9-16.

Research output: Contribution to journalArticle

Yang, D, Fontaine, KR, Wang, C & Allison, DB 2003, 'Weight loss causes increased mortality: Cons', Obesity Reviews, vol. 4, no. 1, pp. 9-16. https://doi.org/10.1046/j.1467-789X.2003.00092.x
Yang, D. ; Fontaine, K. R. ; Wang, C. ; Allison, D. B. / Weight loss causes increased mortality : Cons. In: Obesity Reviews. 2003 ; Vol. 4, No. 1. pp. 9-16.
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