Abstract
The association of wealth and infections with Giardia, Cryptosporidium, Cyclospora, and microsporidia were examined in a longitudinal cohort conducted in Peru from 2001 to 2006. Data from 492 participants were daily clinical manifestations, weekly copro-parasitological diagnosis, and housing characteristics and assets owned (48 variables), and these data were used to construct a global wealth index using principal component analysis. Data were analyzed using continuous and categorical (wealth tertiles) models. Participant's mean age was 3.43 years (range = 0-12 years), with average follow-up of 993 days. Univariate and multivariate analyses identified significant associations between wealth and infections with Giardia and microsporidia. Participants with greater wealth indexes were associated with protection against Giardia (P <0.001) and persistent Giardia infections (> 14 days). For microsporidia, greater wealth was protective (P = 0.066 continuous and P = 0.042 by tertiles). Contrarily, infections with Cryptosporidium and Cyclospora were independent of wealth. Thus, subtle differences in wealth may affect the frequency of specific parasitic infections within low-income communities.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 38-42 |
| Number of pages | 5 |
| Journal | American Journal of Tropical Medicine and Hygiene |
| Volume | 84 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2011 |
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ASJC Scopus subject areas
- Parasitology
- Infectious Diseases
- Virology
- Medicine(all)
Cite this
Wealth and its associations with enteric parasitic infections in a low-income community in Peru : Use of principal component analysis. / Nundy, Shantanu; Gilman, Robert H; Xiao, Lihua; Cabrera, Lilia; Cama, Rosa; Ortega, Ynes R.; Kahn, Geoffrey; Cama, Vitaliano A.
In: American Journal of Tropical Medicine and Hygiene, Vol. 84, No. 1, 01.2011, p. 38-42.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Wealth and its associations with enteric parasitic infections in a low-income community in Peru
T2 - Use of principal component analysis
AU - Nundy, Shantanu
AU - Gilman, Robert H
AU - Xiao, Lihua
AU - Cabrera, Lilia
AU - Cama, Rosa
AU - Ortega, Ynes R.
AU - Kahn, Geoffrey
AU - Cama, Vitaliano A.
PY - 2011/1
Y1 - 2011/1
N2 - The association of wealth and infections with Giardia, Cryptosporidium, Cyclospora, and microsporidia were examined in a longitudinal cohort conducted in Peru from 2001 to 2006. Data from 492 participants were daily clinical manifestations, weekly copro-parasitological diagnosis, and housing characteristics and assets owned (48 variables), and these data were used to construct a global wealth index using principal component analysis. Data were analyzed using continuous and categorical (wealth tertiles) models. Participant's mean age was 3.43 years (range = 0-12 years), with average follow-up of 993 days. Univariate and multivariate analyses identified significant associations between wealth and infections with Giardia and microsporidia. Participants with greater wealth indexes were associated with protection against Giardia (P <0.001) and persistent Giardia infections (> 14 days). For microsporidia, greater wealth was protective (P = 0.066 continuous and P = 0.042 by tertiles). Contrarily, infections with Cryptosporidium and Cyclospora were independent of wealth. Thus, subtle differences in wealth may affect the frequency of specific parasitic infections within low-income communities.
AB - The association of wealth and infections with Giardia, Cryptosporidium, Cyclospora, and microsporidia were examined in a longitudinal cohort conducted in Peru from 2001 to 2006. Data from 492 participants were daily clinical manifestations, weekly copro-parasitological diagnosis, and housing characteristics and assets owned (48 variables), and these data were used to construct a global wealth index using principal component analysis. Data were analyzed using continuous and categorical (wealth tertiles) models. Participant's mean age was 3.43 years (range = 0-12 years), with average follow-up of 993 days. Univariate and multivariate analyses identified significant associations between wealth and infections with Giardia and microsporidia. Participants with greater wealth indexes were associated with protection against Giardia (P <0.001) and persistent Giardia infections (> 14 days). For microsporidia, greater wealth was protective (P = 0.066 continuous and P = 0.042 by tertiles). Contrarily, infections with Cryptosporidium and Cyclospora were independent of wealth. Thus, subtle differences in wealth may affect the frequency of specific parasitic infections within low-income communities.
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UR - http://www.scopus.com/inward/citedby.url?scp=79952260256&partnerID=8YFLogxK
U2 - 10.4269/ajtmh.2011.10-0442
DO - 10.4269/ajtmh.2011.10-0442
M3 - Article
C2 - 21212198
AN - SCOPUS:79952260256
VL - 84
SP - 38
EP - 42
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
SN - 0002-9637
IS - 1
ER -