TY - JOUR
T1 - Waist-to-Height Ratio as a Predictor of C-Reactive Protein Levels
AU - Giannini, Denise Tavares
AU - Kuschnir, Maria Cristina Caetano
AU - de Oliveira, Cecília Lacroix
AU - Szklo, Moyses
PY - 2017/9/13
Y1 - 2017/9/13
N2 - Background: C-reactive protein is an acute-phase protein that has been found in association with adiposity and cardiovascular disease risk. In this paper, the objective was to assess the relationship of C-reactive protein to four anthropometric measurements: body mass index, waist-to-height ratio, C index, and waist circumference. Methods: A cross-sectional random sample of the Study of Cardiovascular Risk in Adolescents (Portuguese acronym “ERICA”) was included in the study. The analysis was adjusted for the complex sampling design. Poisson regression models with robust variance were used to estimate a multivariate-adjusted prevalence rate ratio expressing the relationship of each anthropometric measure to C-reactive protein. We evaluated adolescents aged 12 to 17 years participating in the capital of Porto Alegre, Brazil. Results: In all, 778 adolescents were included (60% female, 58% aged 15–17 years). Waist-to-height ratio was found to be the strongest adiposity marker associated with C-reactive protein even after adjusting for age, sex, smoking, physical activity, and insulin resistance (prevalence rate ratio = 7.09; 95% confidence interval, 5.01–9.18; p < 0.001). Conclusions: Waist-to-height ratio is a strong predictor of C-reactive protein in adolescents in Porto Alegre, Brazil.
AB - Background: C-reactive protein is an acute-phase protein that has been found in association with adiposity and cardiovascular disease risk. In this paper, the objective was to assess the relationship of C-reactive protein to four anthropometric measurements: body mass index, waist-to-height ratio, C index, and waist circumference. Methods: A cross-sectional random sample of the Study of Cardiovascular Risk in Adolescents (Portuguese acronym “ERICA”) was included in the study. The analysis was adjusted for the complex sampling design. Poisson regression models with robust variance were used to estimate a multivariate-adjusted prevalence rate ratio expressing the relationship of each anthropometric measure to C-reactive protein. We evaluated adolescents aged 12 to 17 years participating in the capital of Porto Alegre, Brazil. Results: In all, 778 adolescents were included (60% female, 58% aged 15–17 years). Waist-to-height ratio was found to be the strongest adiposity marker associated with C-reactive protein even after adjusting for age, sex, smoking, physical activity, and insulin resistance (prevalence rate ratio = 7.09; 95% confidence interval, 5.01–9.18; p < 0.001). Conclusions: Waist-to-height ratio is a strong predictor of C-reactive protein in adolescents in Porto Alegre, Brazil.
KW - adolescent
KW - Anthropometry
KW - C-reactive protein
KW - cardiovascular disease
KW - insulin resistance
KW - obesity
UR - http://www.scopus.com/inward/record.url?scp=85029501872&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85029501872&partnerID=8YFLogxK
U2 - 10.1080/07315724.2017.1338631
DO - 10.1080/07315724.2017.1338631
M3 - Article
C2 - 28910190
AN - SCOPUS:85029501872
SP - 1
EP - 7
JO - Journal of the American College of Nutrition
JF - Journal of the American College of Nutrition
SN - 0731-5724
ER -