Vulvar hypertrophy with lymphedema: A mimicker of aggressive angiomyxoma

R. Vang, J. H. Connelly, H. A. Hammill, R. L. Shannon

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


We report the case of a 43-year-old quadriplegic woman with bilateral vulvar enlargement. The clinical impression was labial hypertrophy, but the microscopic features mimicked aggressive angiomyxoma because of the location, hypocellular proliferation of fibroblastic cells in an edematous-myxoid stroma, and vessels with perivascular collagen deposition, which simulated the thick-walled vessels of aggressive angiomyxoma. Since the lesion lacked true thickwailed vessels and contained ectatic tortuous lymphatics, the pathologic interpretation was lymphedema. This vulvar lesion should be recognized to prevent the misdiagnosis of aggressive angiomyxoma.

Original languageEnglish (US)
Pages (from-to)1697-1699
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Issue number11
StatePublished - Nov 30 2000
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology


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