Vulvar carcinoma with hypercalcemia

Jennifer R. Niebyl, Rene Genadry, Eduard G. Friedrich, Edward J. Wilkinson, J. Donald Woodruff

Research output: Contribution to journalArticlepeer-review


Hypercalcemia associated with nonmetaslatic malignancy has been reported most frequently with lung or kidney tumors, while among gynecologic malignancies, the ovary has been the most common primary site. The pertinent clinicopathologic features of 2 cases of nonmetastatic vulvar carcinoma producing hypercalcemia are described in the present report. Including 3 previously reported cases, the vulva is seen to be the second must common site in the female genital tract for production of this paraendocrine syndrome. The clinician should be aware of the association of hypercalcemia and mental confusion with bulky vulvar tumors, so that surgery will not needlessly be delayed in a futile attempt to correct the hypercalcemia medically.

Original languageEnglish (US)
Pages (from-to)343-348
Number of pages6
JournalObstetrics and gynecology
Issue number3
StatePublished - Mar 1975

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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