Abstract
A 25-year-old Iranian man had undergone eye wall resection of a large von Hippel angioma to alleviate an exaggerated macular response, affording study by light and electron microscopy and immunohistochemistry before the obfuscatory effects of long-standing exudative retinal detachment, gliosis, or iatrogen ablation supervened. We used this vantage point to assess the interrelation between the component endothelial cells, pericytes, and stromal foam cells. On the basis of staining with glial fibrillary acidic protein, factor VIII, the C3 fraction of complement, fibrinogen, and lysozyme, it is unlikely that stromal foam cells derive from glial precursors, but may represent degenerating cells, perhaps arising from a common vasoformative stem cell under hypoxic stress.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 848-855 |
| Number of pages | 8 |
| Journal | Ophthalmology |
| Volume | 90 |
| Issue number | 7 |
| State | Published - 1983 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
Von Hippel angiomatosis. A light, electron microscopic, and immunoperoxidase characterization. / Mottow Lippa, L.; Tso, M. O M; Peyman, G. A.; Chejfec, G.
In: Ophthalmology, Vol. 90, No. 7, 1983, p. 848-855.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Von Hippel angiomatosis. A light, electron microscopic, and immunoperoxidase characterization
AU - Mottow Lippa, L.
AU - Tso, M. O M
AU - Peyman, G. A.
AU - Chejfec, G.
PY - 1983
Y1 - 1983
N2 - A 25-year-old Iranian man had undergone eye wall resection of a large von Hippel angioma to alleviate an exaggerated macular response, affording study by light and electron microscopy and immunohistochemistry before the obfuscatory effects of long-standing exudative retinal detachment, gliosis, or iatrogen ablation supervened. We used this vantage point to assess the interrelation between the component endothelial cells, pericytes, and stromal foam cells. On the basis of staining with glial fibrillary acidic protein, factor VIII, the C3 fraction of complement, fibrinogen, and lysozyme, it is unlikely that stromal foam cells derive from glial precursors, but may represent degenerating cells, perhaps arising from a common vasoformative stem cell under hypoxic stress.
AB - A 25-year-old Iranian man had undergone eye wall resection of a large von Hippel angioma to alleviate an exaggerated macular response, affording study by light and electron microscopy and immunohistochemistry before the obfuscatory effects of long-standing exudative retinal detachment, gliosis, or iatrogen ablation supervened. We used this vantage point to assess the interrelation between the component endothelial cells, pericytes, and stromal foam cells. On the basis of staining with glial fibrillary acidic protein, factor VIII, the C3 fraction of complement, fibrinogen, and lysozyme, it is unlikely that stromal foam cells derive from glial precursors, but may represent degenerating cells, perhaps arising from a common vasoformative stem cell under hypoxic stress.
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UR - http://www.scopus.com/inward/citedby.url?scp=0020565857&partnerID=8YFLogxK
M3 - Article
C2 - 6353309
AN - SCOPUS:0020565857
VL - 90
SP - 848
EP - 855
JO - Ophthalmology
JF - Ophthalmology
SN - 0161-6420
IS - 7
ER -