Voltage-sensitive Na+ channels: motifs, modes and modulation

Megan Stephan, William Agnew

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Abstract

Much recent progress has been made in understanding the structural organization and functional properties of voltage-dependent Na+ channels, in particular in the areas of activation, ion conductance, and inactivation. At the same time, however, electrophysiological studies have revealed new, more complex functional properties in the form of at least two gating modes and the existence of as yet unidentified modulatory factors.

Original languageEnglish (US)
Pages (from-to)676-684
Number of pages9
JournalCurrent Opinion in Cell Biology
Volume3
Issue number4
DOIs
StatePublished - 1991
Externally publishedYes

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Voltage-sensitive Na+ channels : motifs, modes and modulation. / Stephan, Megan; Agnew, William.

In: Current Opinion in Cell Biology, Vol. 3, No. 4, 1991, p. 676-684.

Research output: Contribution to journalArticle

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