TY - JOUR
T1 - Vitreous Fluorophotometry for Clinical Research
T2 - I. Description and Evaluation of a New Fluorophotometer
AU - Zeimer, Ran C.
AU - Blair, Norman P.
AU - Cunha-Vaz, Jose G.
N1 - Funding Information:
ThisstudywassupportedinpartbyPublic Health Service research grants EY03106 and EY03227(DrBlair)andbyOphthalmicResearch Institute.CenterCore grant EY1792 from the National Eye
PY - 1983/11
Y1 - 1983/11
N2 - In vitro and in vivo tests of a new commercial fluorophotometer showed that the instrument is capable of measuring fluorescein concentrations of 1 to 1,000 ng/mL accurately. The in vivo estimate of the spread functions of the lens and chorioretinal peaks yielded values of about 1% and 0.5% 3 and 6 mm, respectively, from the peak. Pigmentation did not influence the chorioretinal spread function. Reproducibility in vivo was evaluated to be 12%. Furthermore, when compared with other existing fluorophotometers, the new instrument performed superiorly.
AB - In vitro and in vivo tests of a new commercial fluorophotometer showed that the instrument is capable of measuring fluorescein concentrations of 1 to 1,000 ng/mL accurately. The in vivo estimate of the spread functions of the lens and chorioretinal peaks yielded values of about 1% and 0.5% 3 and 6 mm, respectively, from the peak. Pigmentation did not influence the chorioretinal spread function. Reproducibility in vivo was evaluated to be 12%. Furthermore, when compared with other existing fluorophotometers, the new instrument performed superiorly.
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U2 - 10.1001/archopht.1983.01040020755019
DO - 10.1001/archopht.1983.01040020755019
M3 - Article
C2 - 6639432
AN - SCOPUS:0021037465
SN - 0003-9950
VL - 101
SP - 1753
EP - 1756
JO - Archives of ophthalmology
JF - Archives of ophthalmology
IS - 11
ER -