Vitreoretinal degeneration as a sign of generalized connective tissue diseases

Irene H. Maumenee

Research output: Contribution to journalArticlepeer-review

Abstract

Dominant vitreoretinal degeneration was first described by Wagner as a benign ocular condition. This term has since become widely associated with a familial retinal degenerative process accompanied by retinal detachments, even though nobody in the family described by Wagner suffered from a retinal detachment. Vitreoretinal degeneration, often progressing to detachments, occurs also in several distinct bone dysplasias. I have provided a classification of syndromes with vitreoretinal degeneration and its significance as a sign of connective tissue diseases (probably involving type II collagen). In this sense, it is similar to ectopia lentis as a sign of various connective tissue diseases.

Original languageEnglish (US)
Pages (from-to)432-449
Number of pages18
JournalAmerican journal of ophthalmology
Volume88
Issue number3 PART 1
DOIs
StatePublished - Sep 1979

ASJC Scopus subject areas

  • Ophthalmology

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