Vitamin D: Multiple sclerosis risk and disease severity

Gloria Von Geldern; Ellen M. Mowry

doi:10.1079/PAVSNNR20127026

Vitamin D: Multiple sclerosis risk and disease severity

Gloria Von Geldern, Ellen M. Mowry

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

This review seeks to provide a summary of the current evidence examining the relationship between multiple sclerosis (MS) and vitamin D. Both the incidence and the severity of MS have been shown to be influenced by vitamin D levels. Herein, we summarize relevant epidemiological studies. We also provide an overview of the in vitro and animal model experiments that give biological plausibility to the relationship between vitamin D and MS. By providing an up-to-date review about this field, directions for further studies may also become clear.

Original language	English (US)
Article number	26
Pages (from-to)	1-8
Number of pages	8
Journal	CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources
Volume	7
DOIs	https://doi.org/10.1079/PAVSNNR20127026
State	Published - 2012

Keywords

Experimental autoimmune encephalomyelitis
Multiple sclerosis
Prognosis
Risk factors
Vitamin D

ASJC Scopus subject areas

General Veterinary
General Agricultural and Biological Sciences
Nature and Landscape Conservation

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10.1079/PAVSNNR20127026

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abstract = "This review seeks to provide a summary of the current evidence examining the relationship between multiple sclerosis (MS) and vitamin D. Both the incidence and the severity of MS have been shown to be influenced by vitamin D levels. Herein, we summarize relevant epidemiological studies. We also provide an overview of the in vitro and animal model experiments that give biological plausibility to the relationship between vitamin D and MS. By providing an up-to-date review about this field, directions for further studies may also become clear.",

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AB - This review seeks to provide a summary of the current evidence examining the relationship between multiple sclerosis (MS) and vitamin D. Both the incidence and the severity of MS have been shown to be influenced by vitamin D levels. Herein, we summarize relevant epidemiological studies. We also provide an overview of the in vitro and animal model experiments that give biological plausibility to the relationship between vitamin D and MS. By providing an up-to-date review about this field, directions for further studies may also become clear.

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KW - Multiple sclerosis

KW - Prognosis

KW - Risk factors

KW - Vitamin D

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Vitamin D: Multiple sclerosis risk and disease severity

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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