Vitamin D Deficiency in Homebound Elderly Persons

Fred Michael Gloth, Caren M. Gundberg, Bruce W. Hollis, John G. Haddad, Jordan D. Tobin

Research output: Contribution to journalArticle

Abstract

To assess the vitamin D status in homebound, community-dwelling elderly persons; sunlight-deprived elderly nursing home residents; and healthy, ambulatory elderly persons. A cohort analytic study. Of 244 subjects at least 65 years old, 116 subjects (85 women and 31 men) had been confined indoors for at least 6 months, either in private dwellings in the community (the Hopkins Elder Housecall Program) or in a teaching nursing home (The Johns Hopkins Geriatrics Center). The 128 control subjects, a healthy ambulatory group, came from the Baltimore Longitudinal Study on Aging. All subjects were free of diseases or medications that might interfere with their vitamin D status. Serum levels of 25-hydroxyvitamin D (25-OHD) and 1,25-dihydroxyvitamin D (1,25-[OH]2D) were measured in all subjects. In a subgroup of 80 subjects, serum levels of intact parathyroid hormone (PTH), ionized calcium, and osteocalcin and intake of vitamin D (through 3-day food records) were assessed. A randomly selected cohort of sunlight-deprived subjects also had serum levels of vitamin D binding protein measured. In sunlight-deprived subjects overall, the mean 25-OHD level was 30 nmol/L (12 ng/mL) (range, <10 to 77 nmol/L [

Original languageEnglish (US)
Pages (from-to)1683-1686
Number of pages4
JournalJournal of the American Medical Association
Volume274
Issue number21
DOIs
StatePublished - Dec 6 1995
Externally publishedYes

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Homebound Persons
Vitamin D Deficiency
Sunlight
Independent Living
Nursing Homes
Vitamin D
Serum
Vitamin D-Binding Protein
Baltimore
Cholecalciferol
Osteocalcin
Parathyroid Hormone
Geriatrics
Longitudinal Studies
Healthy Volunteers
Teaching
Cohort Studies
Calcium
Food

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Vitamin D Deficiency in Homebound Elderly Persons. / Gloth, Fred Michael; Gundberg, Caren M.; Hollis, Bruce W.; Haddad, John G.; Tobin, Jordan D.

In: Journal of the American Medical Association, Vol. 274, No. 21, 06.12.1995, p. 1683-1686.

Research output: Contribution to journalArticle

Gloth, Fred Michael ; Gundberg, Caren M. ; Hollis, Bruce W. ; Haddad, John G. ; Tobin, Jordan D. / Vitamin D Deficiency in Homebound Elderly Persons. In: Journal of the American Medical Association. 1995 ; Vol. 274, No. 21. pp. 1683-1686.
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