Vitamin A supplementation and growth: A randomized community trial

K. P. West, E. Djunaedi, A. Pandji, Kusdiono, I. Tarwotjo, A. Sommer, A. A. Loedin, I. Satibi, S. Nur, H. Nendrawati, R. Tilden, L. Mele, D. Kraushaar, H. Taylor

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

A randomized community trial was carried out in Aceh, Indonesia, 1982-1984, to assess the impact of semiannual vitamin A (VA) supplementation (60000 μg RE) on preschool child growth: 229 villages were randomized to VA program and 221 to control status. One thousand thirty-two program and 980 control children aged 1-5 y were assessed and followed for 12 mo. VA program males gained an additional ~110 g weight at age 2-3 y (NS), 190 g at age 4 y (p < 0.05), and 263 g at age 5 y over control males (p < 0.01). Arm circumference and muscle area expanded 2 mm (p < 0.05) and ~36 mm2 (p < 0.05) more per year, respectively, from ages 3 to 5 y of age and more arm fat was retained at every age (p < 0.05 at 1 and 3 y) in VA males. There were no group differences in ponderal growth for females or in linear growth for either sex. VA supplementation may improve growth where endemic deficiency exists.

Original languageEnglish (US)
Pages (from-to)1257-1264
Number of pages8
JournalAmerican Journal of Clinical Nutrition
Volume48
Issue number5
DOIs
StatePublished - 1988

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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