Vitamin A-dependent fucose-glycopeptide from rat tracheal epithelium

Fabrizio Bonanni, Luigi De Luca

Research output: Contribution to journalArticle

Abstract

Tracheas from normal and vitamin A-deficient rats were incubated in the presence of l-[3H]fucose and d-[14C]glucosamine to label epithelial and mesenchymal glycoproteins. The epithelium and the cartilage were separated by incubation with testicular hyraluronidase and processed separately for the preparation of glycopeptides. One major epithelial glycopeptide was doubly labeled. In vitamin A deficiency the amount of l-[3H]fucose was reduced to 33% that of the normal. The tracheal fucose-glycopeptide, in molar ratios, contained fucose 1.0, mannonse 1.0, galactose 0.4, hexasamine 4.7, and sialic acid 3.5. Sulfate was absent.

Original languageEnglish (US)
Pages (from-to)632-637
Number of pages6
JournalBBA - General Subjects
Volume343
Issue number3
DOIs
StatePublished - May 24 1974
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology

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