Visualization of infarction using fractional anisotropy

Sahar Soleimanifard, Khaled Z. Abd-Elmoniem, Harsh Agarwal, Miguel S. Tomas, Tetsuo Sasano, Evertjan Vonken, Amr Youssef, M. Roselle Abraham, Theodore P. Abraham, Jerry L. Prince

Research output: Contribution to journalArticlepeer-review


A study was conducted to visualize infarction using fractional anisotropy. The study introduced a scalar index of three-dimensional regional myocardial strain for detection and localization of myocardial infarction. Myocardial infarction (MI) was induced by LAD coronary artery ligation in a pig and gadolinium contrast was performed after infarction and delayed enhancement (DE) viability images were acquired. The zHARP pulse sequence was run on a commercial Philips 3T-Achieva whole body system, yielding 8-10 slices from which midventricular three-dimensional strains were computed. Fractional anisotropy (FA) was evaluated at each voxel for all time frames within one cardiac cycle and the mid-diastolic tagged images were registered to the corresponding DE images, while Harp tracking was used to register the FA occurring at end-systole with the DE intensities observed on the mid-diastolic geometry.

Original languageEnglish (US)
Article numberP153
JournalJournal of Cardiovascular Magnetic Resonance
Issue numberSUPPL. 1
StatePublished - 2010

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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