Visual- and saccade-related signals in the primate inferior colliculus

Kristin Kelly Porter, Ryan R. Metzger, Jennifer M. Groh

Research output: Contribution to journalArticle

Abstract

The inferior colliculus (IC) is normally thought of as a predominantly auditory structure because of its early position in the ascending auditory pathway just before the auditory thalamus. Here, we show that a majority of IC neurons (64% of 180 neurons) in awake monkeys carry visual- and/or saccade-related signals in addition to their auditory responses (P < 0.05). The response patterns involve primarily excitatory visual responses, but also increased activity time-locked to the saccade, slow rises in activity time-locked to the onset of the visual stimulus, and inhibitory responses. The presence of these visual-related signals suggests that the IC plays a role in integrating visual and auditory information. More broadly, our results show that interactions between sensory pathways can occur at very early points in sensory processing streams, which implies that multisensory integration may be a low-level rather than an exclusively high-level process.

Original languageEnglish (US)
Pages (from-to)17855-17860
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Volume104
Issue number45
DOIs
StatePublished - Nov 6 2007

Keywords

  • Auditory
  • Cross-modal
  • Monkey
  • Multisensory
  • Vision

ASJC Scopus subject areas

  • General

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