Visible-light optical coherence tomography for retinal oximetry

Ji Yi; Qing Wei; Wenzhong Liu; Vadim Backman; Hao F. Zhang

doi:10.1364/OL.38.001796

Visible-light optical coherence tomography for retinal oximetry

Ji Yi, Qing Wei, Wenzhong Liu, Vadim Backman, Hao F. Zhang

Research output: Contribution to journal › Article › peer-review

111 Scopus citations

Abstract

We applied a visible-light spectroscopic optical coherence tomography (vis-OCT) for in vivo retinal oximetry. To extract hemoglobin oxygen saturation (sO2) in individual retinal vessels, we established a comprehensive analytical model to describe optical absorption, optical scattering, and blood cell packing factor in the whole blood and fit the acquired vis-OCT signals from the bottom of each imaged vessel. We found that averaged sO2 values in arterial and venous bloods were 95% and 72%, respectively.

Original language	English (US)
Pages (from-to)	1796-1798
Number of pages	3
Journal	Optics Letters
Volume	38
Issue number	11
DOIs	https://doi.org/10.1364/OL.38.001796
State	Published - Jun 1 2013
Externally published	Yes

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

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10.1364/OL.38.001796

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abstract = "We applied a visible-light spectroscopic optical coherence tomography (vis-OCT) for in vivo retinal oximetry. To extract hemoglobin oxygen saturation (sO2) in individual retinal vessels, we established a comprehensive analytical model to describe optical absorption, optical scattering, and blood cell packing factor in the whole blood and fit the acquired vis-OCT signals from the bottom of each imaged vessel. We found that averaged sO2 values in arterial and venous bloods were 95% and 72%, respectively.",

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AU - Yi, Ji

AU - Wei, Qing

AU - Liu, Wenzhong

AU - Backman, Vadim

AU - Zhang, Hao F.

PY - 2013/6/1

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AB - We applied a visible-light spectroscopic optical coherence tomography (vis-OCT) for in vivo retinal oximetry. To extract hemoglobin oxygen saturation (sO2) in individual retinal vessels, we established a comprehensive analytical model to describe optical absorption, optical scattering, and blood cell packing factor in the whole blood and fit the acquired vis-OCT signals from the bottom of each imaged vessel. We found that averaged sO2 values in arterial and venous bloods were 95% and 72%, respectively.

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Visible-light optical coherence tomography for retinal oximetry

Abstract

ASJC Scopus subject areas

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