TY - JOUR
T1 - Viruses as potential targets for therapy in HIV-associated malignancies
AU - Ambinder, Richard F.
PY - 2003/6
Y1 - 2003/6
N2 - Epstein-Barr virus or Kaposi's sarcoma herpesvirus - and, at times, both viruses - are present in the tumor cells of many HIV-associated malignancies. Their presence provides potential therapeutic targets for adoptive immunotherapy with antigen-specific T cells, vaccines to induce specific T-cell responses, and pharmacologic therapies to kill tumor cells or alter their malignant phenotype.
AB - Epstein-Barr virus or Kaposi's sarcoma herpesvirus - and, at times, both viruses - are present in the tumor cells of many HIV-associated malignancies. Their presence provides potential therapeutic targets for adoptive immunotherapy with antigen-specific T cells, vaccines to induce specific T-cell responses, and pharmacologic therapies to kill tumor cells or alter their malignant phenotype.
UR - http://www.scopus.com/inward/record.url?scp=0037711547&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037711547&partnerID=8YFLogxK
U2 - 10.1016/S0889-8588(03)00045-5
DO - 10.1016/S0889-8588(03)00045-5
M3 - Review article
C2 - 12852651
AN - SCOPUS:0037711547
SN - 0889-8588
VL - 17
SP - 697
EP - 702
JO - Hematology/Oncology Clinics of North America
JF - Hematology/Oncology Clinics of North America
IS - 3
ER -