Viruses as potential targets for therapy in HIV-associated malignancies

Research output: Contribution to journalArticle

Abstract

Epstein-Barr virus or Kaposi's sarcoma herpesvirus - and, at times, both viruses - are present in the tumor cells of many HIV-associated malignancies. Their presence provides potential therapeutic targets for adoptive immunotherapy with antigen-specific T cells, vaccines to induce specific T-cell responses, and pharmacologic therapies to kill tumor cells or alter their malignant phenotype.

Original languageEnglish (US)
Pages (from-to)697-702
Number of pages6
JournalHematology/Oncology Clinics of North America
Volume17
Issue number3
StatePublished - Jun 2003

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HIV
Viruses
T-Lymphocytes
Adoptive Immunotherapy
Neoplasms
Kaposi's Sarcoma
Herpesviridae
Human Herpesvirus 4
Therapeutics
Vaccines
Phenotype
Antigens

ASJC Scopus subject areas

  • Oncology
  • Hematology

Cite this

Viruses as potential targets for therapy in HIV-associated malignancies. / Ambinder, Richard F.

In: Hematology/Oncology Clinics of North America, Vol. 17, No. 3, 06.2003, p. 697-702.

Research output: Contribution to journalArticle

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