Virus-specific sequences in nuclear DNA from non-producer hamster Rous sarcoma

E. A. Ratovitski; J. D. Shaposhnikov; V. K. Gaber; P. G. Knyazev

Virus-specific sequences in nuclear DNA from non-producer hamster Rous sarcoma

E. A. Ratovitski, J. D. Shaposhnikov, V. K. Gaber, P. G. Knyazev

Research output: Contribution to journal › Article › peer-review

Abstract

Proviral DNA from non-producer Rous sarcoma in Syrian hamster contains practically all the nucleotide sequences presented in ¹²⁵I-labeled RNA from Rous sarcoma virus, Carr-Zilber strain. Virus-specific sequences consist of moderately reiterated and unique DNA regions. The amount of Rous sarcoma virus-specific provirus equivalents in hamster Rous sarcoma DNA is equal to 5.2 ± 0.01. Experiments on transfection show that proviral DNA studied possesses biological activity in respect to cell transformation and virus production. The infectivity of DNA from hamster tumor does not depend on the expression of group-specific (gs) antigen in the recipient cells.

Original language	English (US)
Pages (from-to)	251-260
Number of pages	10
Journal	Neoplasma
Volume	26
Issue number	3
State	Published - 1979
Externally published	Yes

ASJC Scopus subject areas

Cancer Research

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title = "Virus-specific sequences in nuclear DNA from non-producer hamster Rous sarcoma",

abstract = "Proviral DNA from non-producer Rous sarcoma in Syrian hamster contains practically all the nucleotide sequences presented in 125I-labeled RNA from Rous sarcoma virus, Carr-Zilber strain. Virus-specific sequences consist of moderately reiterated and unique DNA regions. The amount of Rous sarcoma virus-specific provirus equivalents in hamster Rous sarcoma DNA is equal to 5.2 ± 0.01. Experiments on transfection show that proviral DNA studied possesses biological activity in respect to cell transformation and virus production. The infectivity of DNA from hamster tumor does not depend on the expression of group-specific (gs) antigen in the recipient cells.",

author = "Ratovitski, {E. A.} and Shaposhnikov, {J. D.} and Gaber, {V. K.} and Knyazev, {P. G.}",

year = "1979",

language = "English (US)",

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AU - Ratovitski, E. A.

AU - Shaposhnikov, J. D.

AU - Gaber, V. K.

AU - Knyazev, P. G.

PY - 1979

Y1 - 1979

N2 - Proviral DNA from non-producer Rous sarcoma in Syrian hamster contains practically all the nucleotide sequences presented in 125I-labeled RNA from Rous sarcoma virus, Carr-Zilber strain. Virus-specific sequences consist of moderately reiterated and unique DNA regions. The amount of Rous sarcoma virus-specific provirus equivalents in hamster Rous sarcoma DNA is equal to 5.2 ± 0.01. Experiments on transfection show that proviral DNA studied possesses biological activity in respect to cell transformation and virus production. The infectivity of DNA from hamster tumor does not depend on the expression of group-specific (gs) antigen in the recipient cells.

AB - Proviral DNA from non-producer Rous sarcoma in Syrian hamster contains practically all the nucleotide sequences presented in 125I-labeled RNA from Rous sarcoma virus, Carr-Zilber strain. Virus-specific sequences consist of moderately reiterated and unique DNA regions. The amount of Rous sarcoma virus-specific provirus equivalents in hamster Rous sarcoma DNA is equal to 5.2 ± 0.01. Experiments on transfection show that proviral DNA studied possesses biological activity in respect to cell transformation and virus production. The infectivity of DNA from hamster tumor does not depend on the expression of group-specific (gs) antigen in the recipient cells.

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Virus-specific sequences in nuclear DNA from non-producer hamster Rous sarcoma

Abstract

ASJC Scopus subject areas

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