TY - JOUR
T1 - Virulence Properties of Rough and Smooth Strains of Vibrio cholerae O1
AU - Islam, Mohammad Sirajul
AU - Ahsan, Sunjukta
AU - Khan, Sirajul Islam
AU - Ahmed, Qazi Shafi
AU - Rashid, Mohammad Harunur
AU - Islam, Khan M.Nasirul
AU - Sack, Richard Bradley
PY - 2004
Y1 - 2004
N2 - A comparative study was carried out to see the differences in pathogenicity of rough and smooth strains. A total of 10 strains including 5 each of rough and smooth strains of Vibrio cholerae O1 were tested and found positive for toxin production by enzyme-linked immunosorbent assay (ELISA) in Richardson's and AKI media. All the smooth and rough strains, except one, showed a titre of 1:10 and 1:100 in Richardson's and AKI media, respectively. Both types of strains produced enterotoxin in rabbit ileal loop (RIL). The differences in multiplication abilities of smooth and rough strains in RIL were statistically significant (P<0.05). However, these differences in multiplying abilities did not influence the adherence potential or enterotoxin production as there was no significant difference (P>0.05) between these properties. This study demonstrated that the rough strains are equally pathogenic and as important as smooth strains.
AB - A comparative study was carried out to see the differences in pathogenicity of rough and smooth strains. A total of 10 strains including 5 each of rough and smooth strains of Vibrio cholerae O1 were tested and found positive for toxin production by enzyme-linked immunosorbent assay (ELISA) in Richardson's and AKI media. All the smooth and rough strains, except one, showed a titre of 1:10 and 1:100 in Richardson's and AKI media, respectively. Both types of strains produced enterotoxin in rabbit ileal loop (RIL). The differences in multiplication abilities of smooth and rough strains in RIL were statistically significant (P<0.05). However, these differences in multiplying abilities did not influence the adherence potential or enterotoxin production as there was no significant difference (P>0.05) between these properties. This study demonstrated that the rough strains are equally pathogenic and as important as smooth strains.
KW - Rough strains
KW - Smooth strains
KW - Vibrio cholerae O1
KW - Virulence
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U2 - 10.1111/j.1348-0421.2004.tb03518.x
DO - 10.1111/j.1348-0421.2004.tb03518.x
M3 - Article
C2 - 15107532
AN - SCOPUS:1942517937
SN - 0385-5600
VL - 48
SP - 229
EP - 235
JO - Microbiology and Immunology
JF - Microbiology and Immunology
IS - 4
ER -