Viral load response to a pneumococcal conjugate vaccine, polysaccharide vaccine or placebo among HIV-infected patients

Matthew Bidwell Goetz, Daniel R. Feikin, Jeffrey L. Lennox, William A. O'Brien, Cheryl M. Elie, Jay C. Butler, Robert F. Breiman

Research output: Contribution to journalArticlepeer-review

Abstract

We determined the HIV viral load in 66 adults randomly assigned to receive pneumococcal immunization with one or two doses of protein conjugate vaccine, one dose of polysaccharide vaccine, one dose of each, or placebo. Second doses were given 8 weeks after the first. Mean baseline viral load and CD4 cell count were 3.41 copies/ml (log10) and 457 cells/μl, respectively. We found no change in viral load during 24 weeks of follow-up for any vaccine or combination of vaccines or placebo.

Original languageEnglish (US)
Pages (from-to)1421-1423
Number of pages3
JournalAIDS
Volume16
Issue number10
DOIs
StatePublished - Jul 5 2002
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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