Viral infections in interferon-γ receptor deficiency

S. E. Dorman, G. Uzel, J. Roesler, J. S. Bradley, J. Bastian, G. Billman, S. King, A. Filie, J. Schermerborn, S. M. Holland

Research output: Contribution to journalArticle

Abstract

Interferon-γ receptor deficiency is a recently described immunodeficiency that is associated with onset of severe mycobacterial infections in childhood. We describe the occurrence of symptomatic and often severe vital infections in 4 patients with interferon-γ receptor deficiency and mycobacterial disease. The vital pathogens included herpes viruses, parainfluenza virus type 3, and respiratory syncytial virus. We conclude that patients with interferon-γ receptor deficiency and mycobacterial disease have increased susceptibility to some vital pathogens.

Original languageEnglish (US)
Pages (from-to)640-643
Number of pages4
JournalJournal of Pediatrics
Volume135
Issue number5
DOIs
StatePublished - 1999

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Dorman, S. E., Uzel, G., Roesler, J., Bradley, J. S., Bastian, J., Billman, G., King, S., Filie, A., Schermerborn, J., & Holland, S. M. (1999). Viral infections in interferon-γ receptor deficiency. Journal of Pediatrics, 135(5), 640-643. https://doi.org/10.1016/S0022-3476(99)70064-8