Viral etiology of pneumonia in a cohort of newborns till 24 months of age in Rural Mirzapur, Bangladesh

Khundkar Hasan, Pauline Jolly, Grace Marquis, Eliza Roy, Goutam Podder, Khorshed Alam, Fazlul Huq, Richard Sack

Research output: Contribution to journalArticle

Abstract

Limited information is available on the etiology of acute lower respiratory infection (ALRI) particularly pneumonia in the rural community of developing countries since most etiological studies are carried out in the hospital settings. This study examined the etiology of pneumonia among young children in a rural community of Bangladesh. A cohort of 252 newborns was followed till 24 months of age during 1993-1996. Community health workers (CHWs) identified cases of ALRI during household surveillance and recommended hospitalization. On admission, nasopharyngeal aspirates (NPA) and blood were collected for bacterial and viral identification, and chest x-rays were done. Multiple regression analysis identified factors associated with a viral etiology. Physicians diagnosed 67 pneumonia; 45% of NPA were positive for viral agents of pneumonia, and respiratory syncytial virus (RSV) was predominant (81%); 6 of 48 blood cultures were positive. X-ray was done for 58 cases; 52% had pneumonic consolidation. Of the RSV cases, 33% were found in children without pneumonic consolidation. Children living in a one-room house were 3 times more likely to develop viral pneumonia (odds ratio (OR) = 3.67, CI 1.05-12.83) than children living in a larger house. Counseling on avoiding crowding where a newborn is accommodated might reduce pneumonia incidence.

Original languageEnglish (US)
Pages (from-to)690-695
Number of pages6
JournalScandinavian Journal of Infectious Diseases
Volume38
Issue number8
DOIs
StatePublished - Aug 2006

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Viral Pneumonia
Bangladesh
Pneumonia
Newborn Infant
Respiratory Syncytial Viruses
Rural Population
Respiratory Tract Infections
X-Rays
Lung
Crowding
Developing Countries
Counseling
Hospitalization
Thorax
Odds Ratio
Regression Analysis
Physicians
Incidence

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

Cite this

Viral etiology of pneumonia in a cohort of newborns till 24 months of age in Rural Mirzapur, Bangladesh. / Hasan, Khundkar; Jolly, Pauline; Marquis, Grace; Roy, Eliza; Podder, Goutam; Alam, Khorshed; Huq, Fazlul; Sack, Richard.

In: Scandinavian Journal of Infectious Diseases, Vol. 38, No. 8, 08.2006, p. 690-695.

Research output: Contribution to journalArticle

Hasan, Khundkar ; Jolly, Pauline ; Marquis, Grace ; Roy, Eliza ; Podder, Goutam ; Alam, Khorshed ; Huq, Fazlul ; Sack, Richard. / Viral etiology of pneumonia in a cohort of newborns till 24 months of age in Rural Mirzapur, Bangladesh. In: Scandinavian Journal of Infectious Diseases. 2006 ; Vol. 38, No. 8. pp. 690-695.
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