Viewing the bilayer hydrocarbon core using neutron diffraction

Research output: Contribution to journalArticle

Abstract

Membrane proteins fold, assemble and function within their native fluid lipid environment. Structural studies of fluid lipid bilayers are thus critically important for understanding processes in membranes. Here, we propose a simple approach to visualize the hydrocarbon core using neutron diffraction and deuterated lipids that are commercially available. This method should have broad utility in structural studies of the bilayer response to protein insertion and folding in membranes.

Original languageEnglish (US)
Pages (from-to)123-131
Number of pages9
JournalJournal of Membrane Biology
Volume227
Issue number3
DOIs
StatePublished - Feb 1 2009

Keywords

  • Biophysical techniques in membrane research
  • Membrane biophysics
  • Membrane structure

ASJC Scopus subject areas

  • Biophysics
  • Physiology
  • Cell Biology

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