Abstract
Membrane proteins fold, assemble and function within their native fluid lipid environment. Structural studies of fluid lipid bilayers are thus critically important for understanding processes in membranes. Here, we propose a simple approach to visualize the hydrocarbon core using neutron diffraction and deuterated lipids that are commercially available. This method should have broad utility in structural studies of the bilayer response to protein insertion and folding in membranes.
Original language | English (US) |
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Pages (from-to) | 123-131 |
Number of pages | 9 |
Journal | Journal of Membrane Biology |
Volume | 227 |
Issue number | 3 |
DOIs | |
State | Published - Feb 2009 |
Keywords
- Biophysical techniques in membrane research
- Membrane biophysics
- Membrane structure
ASJC Scopus subject areas
- Biophysics
- Physiology
- Cell Biology