TY - JOUR
T1 - Victimization in Early Adolescence, Stress, and Depressive Symptoms among Aging Sexual Minority Men
T2 - Findings from the Multicenter AIDS Cohort Study
AU - Surkan, Pamela J.
AU - Wang, Ruibin
AU - Huang, Yuru
AU - Stall, Ron
AU - Plankey, Michael
AU - Teplin, Linda A.
AU - Wight, Richard G.
AU - Jacobson, Lisa P.
AU - Abraham, Alison G.
N1 - Publisher Copyright:
© 2020, Mary Ann Liebert, Inc.
PY - 2020/4
Y1 - 2020/4
N2 - Purpose: We investigated the relation between adversities in early adolescence and risk of a depressive phenotype in adulthood, and whether stress in adulthood modified these associations. Methods: A total of 1138 men who have sex with men (MSM) participated in a Multicenter AIDS Cohort substudy in which they reported on adversities in early adolescence. Poisson regression estimated prevalence ratios (PRs) for associations between adversities and a depressive phenotype in adulthood. Stratified analyses examined the effects of stress in the last year on the depressive phenotype. Results: In adjusted models, men who were verbally insulted; threatened by physical violence; had an object thrown at them; or punched, kicked, or beaten were at higher risk of having a depressive phenotype in adulthood (for ≥1 time per month vs. never, PR = 1.50, 95% confidence interval [CI] = 1.15-1.96; PR = 1.84, 95% CI = 1.45-2.34; PR = 2.00, 95% CI = 1.51-2.66; or PR = 1.78, 95% CI = 1.35-2.34, respectively.) Being threatened with a weapon approached statistical significance (PR = 1.89, 95% CI = 0.96-3.72). Although higher stress was associated with depression overall, early adolescent victimization was only associated with depression among MSM not reporting high levels of stress in the last year (for ≥1 time per month vs. never, PR = 1.68, 95% CI = 1.09-2.59; PR = 2.11, 95% CI = 1.40-3.17; PR = 2.24, 95% CI = 1.24-4.03; PR = 1.98, 95% CI = 1.22-3.22, respectively). Conclusion: The attenuation of relationships between adversities and depression among men reporting high stress may suggest that adult stress overshadows long-term effects of early adolescent victimization on adult depression. Victimization in early adolescence may increase the risk of sustained depressive symptoms in mid- to later life, reinforcing the need for preventive strategies.
AB - Purpose: We investigated the relation between adversities in early adolescence and risk of a depressive phenotype in adulthood, and whether stress in adulthood modified these associations. Methods: A total of 1138 men who have sex with men (MSM) participated in a Multicenter AIDS Cohort substudy in which they reported on adversities in early adolescence. Poisson regression estimated prevalence ratios (PRs) for associations between adversities and a depressive phenotype in adulthood. Stratified analyses examined the effects of stress in the last year on the depressive phenotype. Results: In adjusted models, men who were verbally insulted; threatened by physical violence; had an object thrown at them; or punched, kicked, or beaten were at higher risk of having a depressive phenotype in adulthood (for ≥1 time per month vs. never, PR = 1.50, 95% confidence interval [CI] = 1.15-1.96; PR = 1.84, 95% CI = 1.45-2.34; PR = 2.00, 95% CI = 1.51-2.66; or PR = 1.78, 95% CI = 1.35-2.34, respectively.) Being threatened with a weapon approached statistical significance (PR = 1.89, 95% CI = 0.96-3.72). Although higher stress was associated with depression overall, early adolescent victimization was only associated with depression among MSM not reporting high levels of stress in the last year (for ≥1 time per month vs. never, PR = 1.68, 95% CI = 1.09-2.59; PR = 2.11, 95% CI = 1.40-3.17; PR = 2.24, 95% CI = 1.24-4.03; PR = 1.98, 95% CI = 1.22-3.22, respectively). Conclusion: The attenuation of relationships between adversities and depression among men reporting high stress may suggest that adult stress overshadows long-term effects of early adolescent victimization on adult depression. Victimization in early adolescence may increase the risk of sustained depressive symptoms in mid- to later life, reinforcing the need for preventive strategies.
KW - HIV
KW - MSM
KW - depression
KW - early adolescence
KW - stress victimization
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UR - http://www.scopus.com/inward/citedby.url?scp=85083073145&partnerID=8YFLogxK
U2 - 10.1089/lgbt.2019.0036
DO - 10.1089/lgbt.2019.0036
M3 - Article
C2 - 32186958
AN - SCOPUS:85083073145
SN - 2325-8292
VL - 7
SP - 155
EP - 165
JO - LGBT health
JF - LGBT health
IS - 3
ER -