Vibrio cholerae O139: How great is the threat of a pandemic?

A. K. Siddique, K. Akram, K. Zaman, P. Mutsuddy, A. Eusof, R. B. Sack

Research output: Contribution to journalArticle

Abstract

The emergence of the new strain Vibrio cholerae O139 and its rapid spread in Bangladesh and India together with its detection in several other countries, have raised the question whether this constitutes the beginning of the eighth pandemic of cholera, and if so, how large a threat it poses. In an attempt to answer this question, epidemic spread patterns of Vibrio cholerae O139 strain in Bangladesh were studied. Initially the epidemic moved quickly and affected the entire coastal and estuarine tidal plains of southern Bangladesh. In the flood plains of the northern regions it affected mostly the north-eastern and north-central areas, at a slower pace than in the southern areas. In the beginning the new strain totally displaced both biotypes (classic and El Tor) of Vibrio cholerae O1. Nearly 2 years after its initial detection, striking differences in the distribution of V. cholerae O139 and O1 were observed. In most northern areas, the new strain was replaced by V. cholerae O1, whereas in the southern coastal regions, the O139 strain continues to dominate epidemics. The study suggests that the O139 strain may become endemic in the coastal ecosystem. The threat of a pandemic, therefore, may not be as large as it first seemed.

Original languageEnglish (US)
Pages (from-to)393-398
Number of pages6
JournalTropical Medicine and International Health
Volume1
Issue number3
StatePublished - 1996

Fingerprint

Vibrio cholerae O139
Vibrio cholerae O1
Bangladesh
Pandemics
Cholera
Ecosystem
India

Keywords

  • Bangladesh
  • cholera
  • epidemics
  • Vibrio cholerae

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Parasitology
  • Immunology

Cite this

Siddique, A. K., Akram, K., Zaman, K., Mutsuddy, P., Eusof, A., & Sack, R. B. (1996). Vibrio cholerae O139: How great is the threat of a pandemic? Tropical Medicine and International Health, 1(3), 393-398.

Vibrio cholerae O139 : How great is the threat of a pandemic? / Siddique, A. K.; Akram, K.; Zaman, K.; Mutsuddy, P.; Eusof, A.; Sack, R. B.

In: Tropical Medicine and International Health, Vol. 1, No. 3, 1996, p. 393-398.

Research output: Contribution to journalArticle

Siddique, AK, Akram, K, Zaman, K, Mutsuddy, P, Eusof, A & Sack, RB 1996, 'Vibrio cholerae O139: How great is the threat of a pandemic?', Tropical Medicine and International Health, vol. 1, no. 3, pp. 393-398.
Siddique AK, Akram K, Zaman K, Mutsuddy P, Eusof A, Sack RB. Vibrio cholerae O139: How great is the threat of a pandemic? Tropical Medicine and International Health. 1996;1(3):393-398.
Siddique, A. K. ; Akram, K. ; Zaman, K. ; Mutsuddy, P. ; Eusof, A. ; Sack, R. B. / Vibrio cholerae O139 : How great is the threat of a pandemic?. In: Tropical Medicine and International Health. 1996 ; Vol. 1, No. 3. pp. 393-398.
@article{a7774d6fcac949a4aa91bc70d85ffd57,
title = "Vibrio cholerae O139: How great is the threat of a pandemic?",
abstract = "The emergence of the new strain Vibrio cholerae O139 and its rapid spread in Bangladesh and India together with its detection in several other countries, have raised the question whether this constitutes the beginning of the eighth pandemic of cholera, and if so, how large a threat it poses. In an attempt to answer this question, epidemic spread patterns of Vibrio cholerae O139 strain in Bangladesh were studied. Initially the epidemic moved quickly and affected the entire coastal and estuarine tidal plains of southern Bangladesh. In the flood plains of the northern regions it affected mostly the north-eastern and north-central areas, at a slower pace than in the southern areas. In the beginning the new strain totally displaced both biotypes (classic and El Tor) of Vibrio cholerae O1. Nearly 2 years after its initial detection, striking differences in the distribution of V. cholerae O139 and O1 were observed. In most northern areas, the new strain was replaced by V. cholerae O1, whereas in the southern coastal regions, the O139 strain continues to dominate epidemics. The study suggests that the O139 strain may become endemic in the coastal ecosystem. The threat of a pandemic, therefore, may not be as large as it first seemed.",
keywords = "Bangladesh, cholera, epidemics, Vibrio cholerae",
author = "Siddique, {A. K.} and K. Akram and K. Zaman and P. Mutsuddy and A. Eusof and Sack, {R. B.}",
year = "1996",
language = "English (US)",
volume = "1",
pages = "393--398",
journal = "Tropical Medicine and International Health",
issn = "1360-2276",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Vibrio cholerae O139

T2 - How great is the threat of a pandemic?

AU - Siddique, A. K.

AU - Akram, K.

AU - Zaman, K.

AU - Mutsuddy, P.

AU - Eusof, A.

AU - Sack, R. B.

PY - 1996

Y1 - 1996

N2 - The emergence of the new strain Vibrio cholerae O139 and its rapid spread in Bangladesh and India together with its detection in several other countries, have raised the question whether this constitutes the beginning of the eighth pandemic of cholera, and if so, how large a threat it poses. In an attempt to answer this question, epidemic spread patterns of Vibrio cholerae O139 strain in Bangladesh were studied. Initially the epidemic moved quickly and affected the entire coastal and estuarine tidal plains of southern Bangladesh. In the flood plains of the northern regions it affected mostly the north-eastern and north-central areas, at a slower pace than in the southern areas. In the beginning the new strain totally displaced both biotypes (classic and El Tor) of Vibrio cholerae O1. Nearly 2 years after its initial detection, striking differences in the distribution of V. cholerae O139 and O1 were observed. In most northern areas, the new strain was replaced by V. cholerae O1, whereas in the southern coastal regions, the O139 strain continues to dominate epidemics. The study suggests that the O139 strain may become endemic in the coastal ecosystem. The threat of a pandemic, therefore, may not be as large as it first seemed.

AB - The emergence of the new strain Vibrio cholerae O139 and its rapid spread in Bangladesh and India together with its detection in several other countries, have raised the question whether this constitutes the beginning of the eighth pandemic of cholera, and if so, how large a threat it poses. In an attempt to answer this question, epidemic spread patterns of Vibrio cholerae O139 strain in Bangladesh were studied. Initially the epidemic moved quickly and affected the entire coastal and estuarine tidal plains of southern Bangladesh. In the flood plains of the northern regions it affected mostly the north-eastern and north-central areas, at a slower pace than in the southern areas. In the beginning the new strain totally displaced both biotypes (classic and El Tor) of Vibrio cholerae O1. Nearly 2 years after its initial detection, striking differences in the distribution of V. cholerae O139 and O1 were observed. In most northern areas, the new strain was replaced by V. cholerae O1, whereas in the southern coastal regions, the O139 strain continues to dominate epidemics. The study suggests that the O139 strain may become endemic in the coastal ecosystem. The threat of a pandemic, therefore, may not be as large as it first seemed.

KW - Bangladesh

KW - cholera

KW - epidemics

KW - Vibrio cholerae

UR - http://www.scopus.com/inward/record.url?scp=0029669883&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029669883&partnerID=8YFLogxK

M3 - Article

C2 - 8673845

AN - SCOPUS:0029669883

VL - 1

SP - 393

EP - 398

JO - Tropical Medicine and International Health

JF - Tropical Medicine and International Health

SN - 1360-2276

IS - 3

ER -