Viable neurons with luxury perfusion in hydrocephalus

Ching Yee Oliver Wong; Mark G. Luciano; William J. MacIntyre; Richard C. Brunken; Joseph F. Hahn; Raymundo T. Go

Viable neurons with luxury perfusion in hydrocephalus

Ching Yee Oliver Wong, Mark G. Luciano, William J. MacIntyre, Richard C. Brunken, Joseph F. Hahn, Raymundo T. Go

Research output: Contribution to journal › Article › peer-review

Abstract

A woman with hydrocephalus due to aqueductal stenosis had functional imaging of cerebral perfusion and metabolism to demonstrate the effects of endoscopic third ventriculostomy-a new form of internal surgical shunting. Technetium-99m-ECD SPECT and ¹⁸FFDG PET showed regional luxury perfusion at the left frontal region. Three months after a successful third ventriculostomy, a repeated imaging of cerebral perfusion and metabolism showed resolution of luxury perfusion and global improvement of both perfusion and metabolism. This concurred with postoperative clinical improvement. The paired imaging of cerebral perfusion and metabolism provides more information than just imaging perfusion or metabolism. Thus, the detection of perfusion and metabolism mismatch may open a new window of opportunity for surgical intervention.

Original language	English (US)
Pages (from-to)	1467-1470
Number of pages	4
Journal	Journal of Nuclear Medicine
Volume	38
Issue number	9
State	Published - Sep 1 1997
Externally published	Yes

Keywords

Hydrocephalus
Perfusion and metabolism mismatch

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Cite this

@article{fb1107de637c4da7b73298f259fe0714,

title = "Viable neurons with luxury perfusion in hydrocephalus",

abstract = "A woman with hydrocephalus due to aqueductal stenosis had functional imaging of cerebral perfusion and metabolism to demonstrate the effects of endoscopic third ventriculostomy-a new form of internal surgical shunting. Technetium-99m-ECD SPECT and 18FFDG PET showed regional luxury perfusion at the left frontal region. Three months after a successful third ventriculostomy, a repeated imaging of cerebral perfusion and metabolism showed resolution of luxury perfusion and global improvement of both perfusion and metabolism. This concurred with postoperative clinical improvement. The paired imaging of cerebral perfusion and metabolism provides more information than just imaging perfusion or metabolism. Thus, the detection of perfusion and metabolism mismatch may open a new window of opportunity for surgical intervention.",

keywords = "Hydrocephalus, Perfusion and metabolism mismatch",

author = "Wong, {Ching Yee Oliver} and Luciano, {Mark G.} and MacIntyre, {William J.} and Brunken, {Richard C.} and Hahn, {Joseph F.} and Go, {Raymundo T.}",

year = "1997",

month = sep,

day = "1",

language = "English (US)",

volume = "38",

pages = "1467--1470",

journal = "Journal of Nuclear Medicine",

issn = "0161-5505",

publisher = "Society of Nuclear Medicine Inc.",

number = "9",

}

TY - JOUR

T1 - Viable neurons with luxury perfusion in hydrocephalus

AU - Wong, Ching Yee Oliver

AU - Luciano, Mark G.

AU - MacIntyre, William J.

AU - Brunken, Richard C.

AU - Hahn, Joseph F.

AU - Go, Raymundo T.

PY - 1997/9/1

Y1 - 1997/9/1

N2 - A woman with hydrocephalus due to aqueductal stenosis had functional imaging of cerebral perfusion and metabolism to demonstrate the effects of endoscopic third ventriculostomy-a new form of internal surgical shunting. Technetium-99m-ECD SPECT and 18FFDG PET showed regional luxury perfusion at the left frontal region. Three months after a successful third ventriculostomy, a repeated imaging of cerebral perfusion and metabolism showed resolution of luxury perfusion and global improvement of both perfusion and metabolism. This concurred with postoperative clinical improvement. The paired imaging of cerebral perfusion and metabolism provides more information than just imaging perfusion or metabolism. Thus, the detection of perfusion and metabolism mismatch may open a new window of opportunity for surgical intervention.

AB - A woman with hydrocephalus due to aqueductal stenosis had functional imaging of cerebral perfusion and metabolism to demonstrate the effects of endoscopic third ventriculostomy-a new form of internal surgical shunting. Technetium-99m-ECD SPECT and 18FFDG PET showed regional luxury perfusion at the left frontal region. Three months after a successful third ventriculostomy, a repeated imaging of cerebral perfusion and metabolism showed resolution of luxury perfusion and global improvement of both perfusion and metabolism. This concurred with postoperative clinical improvement. The paired imaging of cerebral perfusion and metabolism provides more information than just imaging perfusion or metabolism. Thus, the detection of perfusion and metabolism mismatch may open a new window of opportunity for surgical intervention.

KW - Hydrocephalus

KW - Perfusion and metabolism mismatch

UR - http://www.scopus.com/inward/record.url?scp=0030884887&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030884887&partnerID=8YFLogxK

M3 - Article

C2 - 9293810

AN - SCOPUS:0030884887

SN - 0161-5505

VL - 38

SP - 1467

EP - 1470

JO - Journal of Nuclear Medicine

JF - Journal of Nuclear Medicine

IS - 9

ER -

Viable neurons with luxury perfusion in hydrocephalus

Abstract

Keywords

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this