Vi SEROLOGY IN DETECTION OF CHRONIC SALMONELLA TYPHI CARRIERS IN AN ENDEMIC AREA

Claudio F. Lanata; Conrado Ristori; Luis Jimenez; Julio Garcia; Myron M. Levine; Robert E. Black; Mario Salcedo; Viviana Sotomayor

doi:10.1016/S0140-6736(83)90401-4

Vi SEROLOGY IN DETECTION OF CHRONIC SALMONELLA TYPHI CARRIERS IN AN ENDEMIC AREA

Claudio F. Lanata, Conrado Ristori, Luis Jimenez, Julio Garcia, Myron M. Levine, Robert E. Black, Mario Salcedo, Viviana Sotomayor

Research output: Contribution to journal › Article

Abstract

A passive haemagglutination assay measuring antibody to highly purified Vi antigen, known to be sensitive and specific for the detection of chronic Salmonella typhi carriers in a non-endemic area, was assessed in an endemic area. A reciprocal serum Vi antibody titre of 160 was found to have a sensitivity of 75%, specificity of 92%, and a high predictive value in screening for chronic S typhi carriers in high-risk population groups (eg, women over 40 years). This simple assay can screen for chronic S typhi carriers even in areas where typhoid fever is highly endemic.

Original language	English (US)
Pages (from-to)	441-443
Number of pages	3
Journal	The Lancet
Volume	322
Issue number	8347
DOIs	https://doi.org/10.1016/S0140-6736(83)90401-4
State	Published - Aug 20 1983
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1016/S0140-6736(83)90401-4

Fingerprint Dive into the research topics of 'Vi SEROLOGY IN DETECTION OF CHRONIC SALMONELLA TYPHI CARRIERS IN AN ENDEMIC AREA'. Together they form a unique fingerprint.

Cite this

Lanata, C. F., Ristori, C., Jimenez, L., Garcia, J., Levine, M. M., Black, R. E., Salcedo, M., & Sotomayor, V. (1983). Vi SEROLOGY IN DETECTION OF CHRONIC SALMONELLA TYPHI CARRIERS IN AN ENDEMIC AREA. The Lancet, 322(8347), 441-443. https://doi.org/10.1016/S0140-6736(83)90401-4

@article{758c64d696fb44eb83590bc0a1e9ce46,

title = "Vi SEROLOGY IN DETECTION OF CHRONIC SALMONELLA TYPHI CARRIERS IN AN ENDEMIC AREA",

abstract = "A passive haemagglutination assay measuring antibody to highly purified Vi antigen, known to be sensitive and specific for the detection of chronic Salmonella typhi carriers in a non-endemic area, was assessed in an endemic area. A reciprocal serum Vi antibody titre of 160 was found to have a sensitivity of 75%, specificity of 92%, and a high predictive value in screening for chronic S typhi carriers in high-risk population groups (eg, women over 40 years). This simple assay can screen for chronic S typhi carriers even in areas where typhoid fever is highly endemic.",

author = "Lanata, {Claudio F.} and Conrado Ristori and Luis Jimenez and Julio Garcia and Levine, {Myron M.} and Black, {Robert E.} and Mario Salcedo and Viviana Sotomayor",

year = "1983",

month = aug,

day = "20",

doi = "10.1016/S0140-6736(83)90401-4",

language = "English (US)",

volume = "322",

pages = "441--443",

journal = "The Lancet",

issn = "0140-6736",

publisher = "Elsevier Limited",

number = "8347",

}

TY - JOUR

T1 - Vi SEROLOGY IN DETECTION OF CHRONIC SALMONELLA TYPHI CARRIERS IN AN ENDEMIC AREA

AU - Lanata, Claudio F.

AU - Ristori, Conrado

AU - Jimenez, Luis

AU - Garcia, Julio

AU - Levine, Myron M.

AU - Black, Robert E.

AU - Salcedo, Mario

AU - Sotomayor, Viviana

PY - 1983/8/20

Y1 - 1983/8/20

N2 - A passive haemagglutination assay measuring antibody to highly purified Vi antigen, known to be sensitive and specific for the detection of chronic Salmonella typhi carriers in a non-endemic area, was assessed in an endemic area. A reciprocal serum Vi antibody titre of 160 was found to have a sensitivity of 75%, specificity of 92%, and a high predictive value in screening for chronic S typhi carriers in high-risk population groups (eg, women over 40 years). This simple assay can screen for chronic S typhi carriers even in areas where typhoid fever is highly endemic.

AB - A passive haemagglutination assay measuring antibody to highly purified Vi antigen, known to be sensitive and specific for the detection of chronic Salmonella typhi carriers in a non-endemic area, was assessed in an endemic area. A reciprocal serum Vi antibody titre of 160 was found to have a sensitivity of 75%, specificity of 92%, and a high predictive value in screening for chronic S typhi carriers in high-risk population groups (eg, women over 40 years). This simple assay can screen for chronic S typhi carriers even in areas where typhoid fever is highly endemic.

UR - http://www.scopus.com/inward/record.url?scp=0020606030&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020606030&partnerID=8YFLogxK

U2 - 10.1016/S0140-6736(83)90401-4

DO - 10.1016/S0140-6736(83)90401-4

M3 - Article

C2 - 6192305

AN - SCOPUS:0020606030

VL - 322

SP - 441

EP - 443

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 8347

ER -