Vestibulo-ocular reflex pathways in internuclear ophthalmoplegia

Phillip D. Cremer, Americo A. Migliaccio, G. Michael Halmagyi, Ian S. Curthoys

Research output: Contribution to journalArticle

Abstract

We measured the vestibulo-ocular reflex (VOR) during head impulses in a patient with right-sided internuclear ophthalmoplegia. Head impulses are rapid, passive, high-acceleration, low-amplitude head rotations in the direction of a particular semicircular canal (SCC). Adduction of the right eye was abnormally slow during right lateral SCC head impulses. The VOR during left posterior SCC impulses was severely deficient in both eyes, but the VOR during left anterior SCC impulses was only slightly deficient. We suggest that the vertical vestibulo-ocular pathways in humans are connected in SCC-plane coordinates, not the traditional roll and pitch coordinates, and that anterior SCC signals do not travel exclusively in the medial longitudinal fasciculus.

Original languageEnglish (US)
Pages (from-to)529-533
Number of pages5
JournalAnnals of Neurology
Volume45
Issue number4
DOIs
StatePublished - 1999
Externally publishedYes

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Vestibulo-Ocular Reflex
Ocular Motility Disorders
Semicircular Canals
Head
Patient Rights

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Vestibulo-ocular reflex pathways in internuclear ophthalmoplegia. / Cremer, Phillip D.; Migliaccio, Americo A.; Halmagyi, G. Michael; Curthoys, Ian S.

In: Annals of Neurology, Vol. 45, No. 4, 1999, p. 529-533.

Research output: Contribution to journalArticle

Cremer, Phillip D. ; Migliaccio, Americo A. ; Halmagyi, G. Michael ; Curthoys, Ian S. / Vestibulo-ocular reflex pathways in internuclear ophthalmoplegia. In: Annals of Neurology. 1999 ; Vol. 45, No. 4. pp. 529-533.
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