Very early alloantigen-independent trafficking of lymphocytes during ischemic acute kidney injury

M. T. Gandolfo, H. Rabb

Research output: Contribution to journalComment/debate


Lymphocytes play an important role during ischemia-reperfusion injury (IRI). Lai et al. have demonstrated, for the first time, an increase in kidney lymphocytes 1 hour after IRI, a newly identified kidney lymphocyte reservoir, and have confirmed the pathogenic role of lymphocytes by manipulating the sphingosine-1-phosphate (SIP)-sphingosine-1-phosphate type 1 (S1P1) receptor pathway.

Original languageEnglish (US)
Pages (from-to)1193-1195
Number of pages3
JournalKidney international
Issue number12
StatePublished - Jun 2007


ASJC Scopus subject areas

  • Nephrology

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