Vertebrobasilar dolichoectasia associated with Marfan syndrome

Isaac E. Silverman, David M. Berman, Gretchen L. Dike, Gene Y. Sung, Brian Litt, Robert J. Wityk

Research output: Contribution to journalArticlepeer-review

Abstract

We report a 37-year-old woman with Marfan syndrome (MFS) who presented with acute myelopathy secondary to a subdural spinal hematoma. The patient died of a subarachnoid hemorrhage 4 days later. Autopsy showed a markedly ectatic vertebrobasilar system with fragmentation of the internal elastic lamina. Microscopic examination of the aorta similarly showed a fragmented internal elastic lamina. We discuss the implications of our patient's early onset vertebrobasilar dolichoectasia; this intracranial disease represents a rare cause of subarachnoid hemorrhage in MFS.

Original languageEnglish (US)
Pages (from-to)196-198
Number of pages3
JournalJournal of Stroke and Cerebrovascular Diseases
Volume9
Issue number4
DOIs
StatePublished - Jul 2000

Keywords

  • Marfan Syndrome
  • Myelopathy
  • Subarachnoid hemorrage
  • Vertobrobasilar dolichoectasia

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Health Professions(all)

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