Vertebrobasilar dolichoectasia associated with Marfan syndrome

Isaac E. Silverman; David M. Berman; Gretchen L. Dike; Gene Y. Sung; Brian Litt; Robert J. Wityk

doi:10.1053/jscd.2000.7224

Vertebrobasilar dolichoectasia associated with Marfan syndrome

Isaac E. Silverman, David M. Berman, Gretchen L. Dike, Gene Y. Sung, Brian Litt, Robert J. Wityk

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

We report a 37-year-old woman with Marfan syndrome (MFS) who presented with acute myelopathy secondary to a subdural spinal hematoma. The patient died of a subarachnoid hemorrhage 4 days later. Autopsy showed a markedly ectatic vertebrobasilar system with fragmentation of the internal elastic lamina. Microscopic examination of the aorta similarly showed a fragmented internal elastic lamina. We discuss the implications of our patient's early onset vertebrobasilar dolichoectasia; this intracranial disease represents a rare cause of subarachnoid hemorrhage in MFS.

Original language	English (US)
Pages (from-to)	196-198
Number of pages	3
Journal	Journal of Stroke and Cerebrovascular Diseases
Volume	9
Issue number	4
DOIs	https://doi.org/10.1053/jscd.2000.7224
State	Published - Jul 2000

Keywords

Marfan Syndrome
Myelopathy
Subarachnoid hemorrage
Vertobrobasilar dolichoectasia

ASJC Scopus subject areas

Clinical Neurology
Surgery
Health Professions(all)

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10.1053/jscd.2000.7224

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title = "Vertebrobasilar dolichoectasia associated with Marfan syndrome",

abstract = "We report a 37-year-old woman with Marfan syndrome (MFS) who presented with acute myelopathy secondary to a subdural spinal hematoma. The patient died of a subarachnoid hemorrhage 4 days later. Autopsy showed a markedly ectatic vertebrobasilar system with fragmentation of the internal elastic lamina. Microscopic examination of the aorta similarly showed a fragmented internal elastic lamina. We discuss the implications of our patient's early onset vertebrobasilar dolichoectasia; this intracranial disease represents a rare cause of subarachnoid hemorrhage in MFS.",

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AU - Silverman, Isaac E.

AU - Berman, David M.

AU - Dike, Gretchen L.

AU - Sung, Gene Y.

AU - Litt, Brian

AU - Wityk, Robert J.

PY - 2000/7

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AB - We report a 37-year-old woman with Marfan syndrome (MFS) who presented with acute myelopathy secondary to a subdural spinal hematoma. The patient died of a subarachnoid hemorrhage 4 days later. Autopsy showed a markedly ectatic vertebrobasilar system with fragmentation of the internal elastic lamina. Microscopic examination of the aorta similarly showed a fragmented internal elastic lamina. We discuss the implications of our patient's early onset vertebrobasilar dolichoectasia; this intracranial disease represents a rare cause of subarachnoid hemorrhage in MFS.

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KW - Subarachnoid hemorrage

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Vertebrobasilar dolichoectasia associated with Marfan syndrome

Abstract

Keywords

ASJC Scopus subject areas

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